Evidence map›Paper›PMID 40611386›Full record

ReviewThe journal of trauma and acute care surgery2025

Prioritizing circulation over airway in trauma patients with exsanguinating injuries: What you need to know.

Paula Ferrada, Juan Duchesne, Mark Piehl

Abstract readReview
In one paragraph

Review in The journal of trauma and acute care surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Paula FerradaFrom the Chair Department of Surgery, Inova Fairfax Medical Campus, Medical Director Perioperative Services IFMC, Division and System Chief for Trauma and Acute Care Surgery, Inova Healthcare System, University of Virginia School of Medicine, Falls Church, VA (P.F.); Department of Surgery, University of Mississippi, Oxford, Mississippi (J.D.); and Department of Surgery, University of North Carolina, Chapel Hill, NC (M.P.).ORCID 0009-0005-2513-8537
Juan Duchesne
Mark Piehl

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

abstractHemorrhage remains a leading cause of preventable trauma-related mortality, with early resuscitation and hemorrhage control serving as crucial interventions. Emerging evidence suggests that prioritizing circulation before airway (Circulation, Airway, and Breathing [CAB]) during initial resuscitation in patients with exsanguinating injuries can improve survival by avoiding the deleterious effects of postintubation hypotension. This article reviews current evidence supporting the CAB approach and outlines best practices across prehospital, emergency department, and operative settings. Delaying advanced airway management while focusing on immediate hemorrhage control and blood product resuscitation has been associated with decreased 24-hour and 30-day mortality. This review synthesizes findings from recent multicenter trials and literature supporting the CAB paradigm, with practical recommendations for implementation in trauma care systems.

Indexed as

Airway ManagementExsanguinationResuscitationWounds and InjuriesHumans

Identifiers

PMID40611386
PMCPMC12893131

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.