Evidence map›Paper›PMID 40611312›Full record

ArticleJournal of health, population, and nutrition2025

Latent profiles of body composition indices and their associations with cardiovascular diseases, hypertension, and diabetes: results from the Fasa Adult Cohort study (FACS).

Mehdi Sharafi, Fatemeh Sadat Razavi, Najibullah Baeradeh, Pezhman Bagheri, Afsaneh Rousta, Sima Afrashteh, Maryam Shiravani, Elham Haghjoo

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Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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8 authors.

Mehdi SharafiDepartment of Nursing, School of Nursing and Midwifery, Gerash University of Medical Sciences, Gerash, Iran.
Fatemeh Sadat RazaviStudent Research Committee, Fasa University of Medical Sciences, Fasa, Iran.
Najibullah BaeradehDepartment of Public Health, Ferdows Faculty of Medical Sciences, Birjand University of Medical Sciences, Birjand, Iran.
Pezhman BagheriDepartment of Epidemiology and Biostatistics, School of Health, Fasa University of Medical Sciences, Fasa, Iran.
Afsaneh RoustaDepartment of Nursing, School of Nursing and Midwifery, Gerash University of Medical Sciences, Gerash, Iran.
Sima AfrashtehDepartment of Biostatistics and Epidemiology, Faculty of Health and Nutrition, Bushehr University of Medical Sciences, Bushehr, Iran.
Maryam ShiravaniDepartment of Health Services Management, School of Health, Hormozgan University of Medical Sciences, Bandar Abbas, Iran.
Elham HaghjooDepartment of Persian Medicine, Fasa University of Medical Sciences, Fasa, Iran. e_haghjoo_56@yahoo.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundThe body mass index (BMI) is a common obesity indicator; however, it has limitations in distinguishing between muscle and fat and does not consider fat distribution. This study examines the association between the latent profile of body composition indices and cardiovascular diseases, hypertension, and diabetes.

methodThis cross-sectional study utilized baseline data from the Fasa Adult Cohort Study (FACS), which included 4,661 participants aged 35 to 70 years. Body composition indices were assessed using bioelectrical impedance analysis (BIA). Latent profile analysis (LPA) was conducted to identify distinct body composition profiles, and the associations between these profiles and the presence of cardiovascular diseases, hypertension, and diabetes were evaluated using multivariable logistic regression models.

resultsAmong diabetes patients, 151 (26.44%) were male. Additionally, 1,218 (93.26%) of smokers were male. There were significant associations between gender and the prevalence of hypertension, diabetes, metabolic syndrome, and cardiovascular disease. The LPA identified five distinct latent profiles, with profiles characterized by higher body fat percentages demonstrating increased odds of diabetes (OR: 5.64, %95CI: 2.86 -to 11.11) and cardiovascular diseases (OR: 2.19, %95CI: 1.11 to 4.31) compared to a low-risk group. Additionally, profiles with higher body fat metrics were associated with significantly increased odds of hypertension (OR: 8.75, 95% CI: 4.60 to 16.65).

conclusionThe findings emphasize the complex interplay between body composition and the Odds of NCDs, highlighting the importance of detailed body composition assessments in public health initiatives. Understanding these relationships can inform targeted prevention and management strategies for NCDs.

Indexed as

Body CompositionCardiovascular DiseasesDiabetes MellitusHypertensionAdultAgedBody Mass IndexCohort StudiesCross-Sectional StudiesElectric ImpedanceFemaleHumansMaleMetabolic SyndromeMiddle AgedObesityBody compositionCardiovascular diseasesDiabetesHypertensionLatent profile analysis

Identifiers

PMID40611312
PMCPMC12224720

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