Evidence map›Paper›PMID 40611232›Full record

ReviewJournal of health, population, and nutrition2025

Relation between non-dietary cardiovascular health and costs associated with stroke in the US.

Abraham M Enyeji, Chioma Obi, Armarion Stegall, Jordan Davis, Roha Surani, Jayson Forbes, David L Wetzell

Abstract readReview
In one paragraph

Review in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abraham M EnyejiMercer University School of Medicine, Columbus, GA, 31901, USA. enyeji_a@mercer.edu.
Chioma ObiJohns Hopkins University Bloomberg School of Public Health, Baltimore, MD, 21205, USA.
Armarion StegallMercer University School of Medicine, Columbus, GA, 31901, USA.
Jordan DavisMercer University School of Medicine, Columbus, GA, 31901, USA.
Roha SuraniMercer University School of Medicine, Columbus, GA, 31901, USA.
Jayson ForbesDepartment of Public Health, NOVA Southeastern University, Fort Lauderdale, FL, 33328, USA.
David L WetzellDepartment of Economics, Michigan State University, East Lansing, MI, 48824, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStroke poses a significant challenge in terms of mortality and healthcare expenditure in the United States, yet the role of Cardiovascular Health (CVH) metrics in alleviating these costs post-stroke remains insufficiently studied. This research aims to evaluate the effectiveness of CVH as a potential tool for secondary prevention by reducing overall healthcare expenditures associated with stroke.

methodsA comprehensive cross-sectional analysis was conducted utilizing data from the Medical Expenditure Panel Survey (MEPS) collected between 2011 and 2022. The analytic sample consisted of 85,735 U.S. adults aged 45 years and older, including 896 individuals with a self-reported history of stroke in the unweighted sample. Cardiovascular Health (CVH) score, a composite measure based on the American Heart Association's Life's Simple 7 metrics, was used to assess health status. Annual costs were assessed using a generalized linear model with a log link and gamma distribution, followed by a two-part model to account for the presence of both positive and zero costs across disaggregated healthcare categories. The analysis controlled for sociodemographic factors, comorbidity burden, and other relevant covariates, enabling the inclusion of interaction terms to evaluate the impact of variations in CVH on costs between the two populations.

resultsThe analysis indicated that stroke patients faced average annual healthcare expenditures of approximately $76,000, substantially influenced by comorbidity levels as measured by the Grouped Charlson Comorbidity Index (GCCI). Additionally, a one-unit improvement in CVH scores was linked to an estimated reduction of $10,100 ([95% CI, $8,400 - $11,800; p < 0.05]) in healthcare costs. Moreover, the effect of CVH improvements for stroke survivors was comparable to that observed in the non-stroke population.

conclusionsThe financial strain of stroke on overall healthcare expenditures highlights the critical need for effective secondary prevention strategies. ​Focused efforts on enhancing CVH metrics, especially in managing hypertension and diabetes, show promise in reducing medical costs linked to stroke.​ A heightened emphasis on these health determinants can facilitate optimized resource allocation and better health outcomes for stroke survivors.

Indexed as

Cardiovascular DiseasesHealth Care CostsHealth ExpendituresHealth StatusStrokeAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedSecondary PreventionUnited StatesBMI (body mass index)CVD (cardiovascular disease)CVH (cardiovascular health)MEPS (medical expenditure panel survey)Stroke

Identifiers

PMID40611232
PMCPMC12224685

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.