Evidence map›Paper›PMID 40611189›Full record

ArticleJournal of health, population, and nutrition2025

Global, regional, and national lifetime probabilities of urinary tract infections and interstitial nephritis from 1990 to 2021.

Lingfeng Li, Yuhao Li, Yongming Chen, Huiming Hou, Jianye Wang, Ming Liu, Xin Wang, Shengfeng Wang

Abstract read
In one paragraph

Article in Journal of health, population, and nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  4. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lingfeng Li *Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Yuhao Li *Department of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, 100191, China.
Yongming Chen *Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Huiming HouDepartment of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Beijing, China.
Jianye WangBeijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Ming LiuBeijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.
Xin WangDepartment of Urology, Beijing Hospital, National Center of Gerontology, Institute of Geriatric Medicine, Beijing, China. wangxingemini@outlook.com.
Shengfeng WangDepartment of Epidemiology and Biostatistics, School of Public Health, Peking University, Beijing, 100191, China. wangshengfeng@bjmu.edu.cn.

Funding

National Key Research and Development Program of China 2022YFC3602900
6 · The paper itself

Abstract

Urinary tract infections (UTI) and interstitial nephritis (IN) are significant global health concerns, leaving a heavy burden to the healthcare system. UTI is one of the most common infections worldwide and IN is characterized by acute and chronic renal damage. This study aims to quantify the lifetime risk of developing and dying from UTI and IN across 204 countries from 1990 to 2021, utilizing data from the Global Burden of Disease 2021. We employed advanced statistical models, including the adjusted for multiple primaries method, Joinpoint trend analysis, and Autoregressive Integrated Moving Average (ARIMA) models, to assess temporal trends and forecast future risks. Results revealed a global lifetime risk of developing UTI and IN at 93.70% in 2021, with higher risks in females (96.05%) compared to males (77.27%). The global lifetime risk of dying from UTI and IN at 0.50%. High Socio-demographic Index (SDI) regions exhibited higher developing risks, while low-SDI regions showed significant upward trends. Gender disparities were evident, with females consistently experiencing higher risks. The ARIMA model projected a persistent upward trend in UTI and IN risks over the next 3 decades, emphasizing the need for targeted public health interventions. These findings highlight the importance of addressing UTI and IN through improved healthcare infrastructure, early screening, and preventive measures, particularly in high-risk populations and regions.

Indexed as

Global HealthNephritis, InterstitialUrinary Tract InfectionsAdolescentAdultAgedFemaleGlobal Burden of DiseaseHumansMaleMiddle AgedModels, StatisticalRisk FactorsYoung AdultHealth inequityInterstitial nephritisUrinary tract infection

Identifiers

PMID40611189
PMCPMC12224759

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.