Evidence map›Paper›PMID 40611139›Full record

ArticleBMC public health2025

Associations of socioeconomic status and health lifestyles with chronic obstructive pulmonary disease: two nationwide population-based studies.

Siying Liu, Tingting Liu, Cihang Lu, Jiahui Guo, Jie Li, Hanyu Wang, Bingxin You, Qiqiang Guo, Jing Zhang, Yongze Li

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed.

  1. The mediating role of healthy lifestyle in the association between higher socioeconomic status and an increased risk of allergic rhinitis: an analysis of NHANES.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Siying Liu *Department of Endocrinology and Metabolism and the Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, First Hospital of China Medical University, No. 155, Nanjing Bei Street, Shenyang, 110001, P. R. China.
Tingting Liu *Department of Endocrinology and Metabolism and the Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, First Hospital of China Medical University, No. 155, Nanjing Bei Street, Shenyang, 110001, P. R. China.
Cihang LuDepartment of Endocrinology, Shengjing Hospital of China Medical University, Shenyang, China.
Jiahui GuoDepartment of Endocrinology and Metabolism and the Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, First Hospital of China Medical University, No. 155, Nanjing Bei Street, Shenyang, 110001, P. R. China.
Jie LiGlobal Health Research Centre, Guangdong Provincial People's Hospital, Guangdong Academy of Medical Sciences, Southern Medical University, Guangzhou, China.
Hanyu WangDepartment of Endocrinology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Bingxin YouSchool of Management, University College London, London, UK.
Qiqiang GuoHealth Sciences Institute, The College of Basic Medical Science, China Medical University, Shenyang, Liaoning Province, China. qqguo@cmu.edu.cn.
Jing ZhangSchool of Public Health, Shenzhen University Medical School, Shenzhen, China. zhangjing1985zj@163.com.
Yongze LiDepartment of Endocrinology and Metabolism and the Institute of Endocrinology, NHC Key Laboratory of Diagnosis and Treatment of Thyroid Diseases, First Hospital of China Medical University, No. 155, Nanjing Bei Street, Shenyang, 110001, P. R. China. yzli87@cmu.edu.cn.

Funding

National Natural Science Foundation of China 82304201National Natural Science Foundation of China 82470826Natural Science Foundation of Liaoning Province 2023-MSLH-409
6 · The paper itself

Abstract

backgroundLow socioeconomic status (SES) is associated with increased chronic obstructive pulmonary disease (COPD) risk, with smoking and poor diet as major contributing factors. However, the impact of a comprehensive healthy lifestyle as a potential mediator between SES and COPD risk remains understudied.

methodsThis study analyzed data from 32,836 US adults in the NHANES (1999-2020) and 131,872 UK adults in the UK Biobank. SES was assessed via latent class analysis based on income, education, employment, and health insurance (NHANES). SES was categorized into high, middle, and low levels. Healthy lifestyle scores included nonsmoking, no heavy drinking, regular physical activity, and a high-quality diet. Weighted multivariable logistic regression (NHANES) and Cox proportional hazards models (UK Biobank) were used to assess the associations between SES and the prevalence (NHANES) or incidence (UK Biobank) of COPD.

resultsIn the UK Biobank, the incidences of newly diagnosed COPD in the high-, medium-, and low-SES groups were 1.27%, 2.92%, and 6.57%, respectively. In the U.S. NHANES, the prevalence rates of COPD were 2.55%, 2.53%, and 4.50%, respectively. Compared with the highest SES group, a low SES was a risk factor for both the incidence and prevalence of COPD (UK Biobank: HR = 3.27, 95% CI = 2.98 to 3.58; NHANES: OR = 1.61, 95% CI = 1.23 to 2.10). The percentages of the mediation effect of a healthy lifestyle in the UK Biobank and US NHANES were 2.81% and 37.27%, respectively. Additionally, compared with those in the group with the highest SES and the healthiest lifestyle, the risk of COPD incidence and prevalence increased by 950% (HR = 10.50, 95% CI = 9.04 to 12.20) and 641% (OR = 7.41, 95% CI = 5.10 to 10.78), respectively, in the group with the lowest SES and the unhealthiest lifestyle. Risk factor analysis for COPD revealed that, in addition to a low SES (HR = 2.55, 95% CI = 2.39 to 2.72; OR = 2.08, 95% CI = 1.76 to 2.46) and unhealthy lifestyle (HR = 2.92, 95% CI = 2.73 to 3.12; OR = 3.78, 95% CI = 3.13 to 4.57), smoking (HR = 5.23, 95% CI = 4.87 to 5.61; OR = 3.85, 95% CI = 3.23 to 4.59) was the most significant risk factor for COPD.

conclusionsLow SES significantly contributes to COPD risk, but a healthy lifestyle mediating this association. Promoting healthy lifestyle choices and addressing socioeconomic disparities are essential public health strategies for COPD prevention. Additionally, smoking cessation and increased early screening in smokers are strongly recommended.

Indexed as

Healthy LifestyleLife StylePulmonary Disease, Chronic ObstructiveSocial ClassAdultAgedFemaleHumansIncidenceMaleMiddle AgedNutrition SurveysPrevalenceRisk FactorsUnited KingdomUnited StatesChronic obstructive pulmonary diseaseCohort studyLifestyleSocioeconomic status

Identifiers

PMID40611139
PMCPMC12225069

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.