Evidence map›Paper›PMID 40611113›Full record

ArticleBMC surgery2025

Surgical management and outcomes of corrosive esophageal injuries: a prospective study from Sana'a, Yemen.

Mohammed Mohammed Al-Shehari, Yasser Abdurabo Obadiel, Ahmed Hamood Al-Helali, Haitham Mohammed Jowah

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Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Mohammed Mohammed Al-ShehariDepartment of Surgery, Faculty of Medicine and Health Science, Sana'a University, Sana'a City, Yemen.
Yasser Abdurabo ObadielDepartment of Surgery, Faculty of Medicine and Health Science, Sana'a University, Sana'a City, Yemen.
Ahmed Hamood Al-HelaliDepartment of Surgery, Al-Thawra Modern General Hospital, Sana'a City, Yemen.
Haitham Mohammed JowahDepartment of Surgery, Faculty of Medicine and Health Science, Sana'a University, Sana'a City, Yemen. h.jowah@su.edu.ye.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCorrosive esophageal injuries pose a significant health burden in resource-limited settings like Yemen. This study evaluated the demographic patterns, clinical presentations, management strategies, and outcomes of patients with corrosive esophageal injuries at a tertiary hospital in Sana’a, Yemen.

methodsThis prospective single-center study at Al-Thawra Modern General Hospital, Sana’a, Yemen (January 2021–June 2024) enrolled 22 patients with corrosive esophageal injuries. Data on demographics, corrosive agents, clinical features, endoscopic findings, management, and outcomes were analyzed using chi-square tests and ANOVA (p < 0.05).

resultsThe mean patient age was 24.7 ± 17.0 years, with 40.9% (n = 9) under 20 years. Accidental ingestion, primarily acidic agents (68.2%, n = 15), accounted for 90.9% (n = 20) of the cases. Dysphagia was the most common symptom (90.9%, n = 20). Endoscopy revealed Grade 2B injuries in 59.1% (n = 13), using the endoscope unable to pass in 13.6% (n = 3). Strictures developed in 36.4% (n = 8) of patients. Endoscopic dilation (ED) was attempted in 77.3% (n = 17), achieving durable symptomatic improvement in 58.8% (n = 10/17). Surgical interventions, including colonic conduit (n = 6) and gastric pull-up (n = 2), were performed in 36.4% (n = 8). Complications occurred in 45.5% (n = 10), and mortality was 13.6% (n = 3), significantly associated with suicidal ingestion (p = 0.001).

conclusionCorrosive esophageal injuries in Yemen, mostly accidental, affect younger patients and result in high morbidity (45.5%). ED is effective for single strictures, but severe cases often require surgery. Gastric pull-up appeared to have lower complications than colonic conduit in this small cohort, although larger studies are needed to confirm this trend. The elevated mortality rate among suicidal cases highlights the need for mental health support. The small sample size (n = 22) and single-center design limit generalizability, necessitating larger multicenter studies to optimize management strategies.

Indexed as

Burns, ChemicalCausticsEsophagusAdolescentAdultChildEsophageal StenosisEsophagoscopyFemaleHumansMaleMiddle AgedProspective StudiesTreatment OutcomeYemenYoung AdultCausticsAcidic agentsCorrosive esophageal injuriesEndoscopic dilationEsophagectomyGastric pull-upStricture formation

Identifiers

PMID40611113
PMCPMC12232069

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.