Evidence map›Paper›PMID 40611104›Full record

ArticleBMC public health2025

Cancer patients' willingness to trade time for health: factors that affect their decision.

Sharifa Ezat Wan Puteh, Hasyimah Razali, Aniza Ismail, Malina Zulkifli, Ida Normaya Mohd Nasir

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Health related quality of life of patients with breast cancer in Malaysia: evidence from EQ-5D-5L and EORTC QLQ-C30.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sharifa Ezat Wan PutehDepartment of Public Health Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Wilayah Persekutuan Kuala Lumpur, 56000, Malaysia.
Hasyimah RazaliDepartment of Public Health Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Wilayah Persekutuan Kuala Lumpur, 56000, Malaysia. syima1904@gmail.com.
Aniza IsmailDepartment of Public Health Medicine, Faculty of Medicine, Universiti Kebangsaan Malaysia, Jalan Yaacob Latif, Bandar Tun Razak, Cheras, Wilayah Persekutuan Kuala Lumpur, 56000, Malaysia.
Malina ZulkifliSchool of Quantitative Sciences, Universiti Utara Malaysia, UUM Sintok, Kedah, 06010, Malaysia.
Ida Normaya Mohd NasirFaculty of Computer and Mathematical Sciences, Universiti Teknologi MARA (UiTM) Kedah Branches, Campus Sg. Petani, Merbok, 08400, Kedah, Malaysia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCancer is a debilitating condition. Cancer patients may exhibit a willingness to trade time for better health, with the trade-off involving the exchange of certain years in their current health states for a shorter lifespan of full health status. However, the willingness to trade time for health greatly depends on individual factors. While some cancer patients may prioritise longer survival time to celebrate significant life events, some others may opt for improved quality of life over a shorter lifespan to reduce suffering. In many countries, the factors influencing the willingness to trade off time among cancer patients remain underexplored. Therefore, in this study, we aimed to determine the factors associated with the willingness of cancer patients to trade survival time for a better state of health in Malaysia.

methodsThis cross-sectional study utilised an online platform to survey 235 respondents suffering from the three major cancer groups, i.e. breast, colon, and lung cancers. Data collection was conducted between March and December 2022 using the Research Electronic Data Capture (REDCap) application. The time trade-off (TTO) method was used to measure the willingness to trade the time, which reflected the length of life expectancy. Data on the socio-demographic, medical profile, and health status (EQ-5D-5 L) of the patients were gathered.

resultsOut of the 235 cancer patients who participated in this study, 135 (57.6%) expressed a willingness to trade time for better health while 100 (42.6%) were not open to such trade-offs. Univariate analysis revealed statistically significant racial differences in willingness to trade length of life. In contrast, age, gender, level of education, household income, insurance coverage, employment status and medical profile characteristics were all not significantly associated with willingness to trade time. The dimensions of self-care and anxiety/depression under EQ-5D-5 L were significantly associated with willingness to trade time (p < 0.05).

conclusionsIn this study, race, self-care, and anxiety/depression were the main factors affecting the willingness to trade time in the Malaysian cancer patient population. These factors significantly influenced their choices on survival time trade-offs. The identification of these factors will help healthcare providers to better align cancer treatment with patients' wellbeing and long-term goals.

Indexed as

Decision MakingNeoplasmsAdultAgedCross-Sectional StudiesFemaleHealth StatusHumansLife ExpectancyMalaysiaMaleMiddle AgedQuality of LifeSurveys and QuestionnairesTime FactorsCancerEQ-5D-5LHealth statusTime trade-off

Identifiers

PMID40611104
PMCPMC12224506

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.