Evidence map›Paper›PMID 40611080›Full record

ArticleBMC public health2025

"We have our reasons": Exploring the acceptability of pre-exposure prophylaxis among gay, bisexual, and other men who have sex with men in Ghana.

Gloria Aidoo-Frimpong, Gamji Rabiu Abu-Ba'are, Amos Apreku, Richard Panix Amoh-Otu, Edem Zigah, Prince Amu-Adu, Samuel Amuah, Laura Nyblade, Kwasi Torpey, LaRon E Nelson

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors.

Gloria Aidoo-FrimpongDepartment of Epidemiology and Environmental Health, University at Buffalo, 193 Farber Hall, Buffalo, NY, 14214, USA. gloriaai@buffalo.edu.ORCID http://orcid.org/0000-0002-4658-2953
Gamji Rabiu Abu-Ba'areCenter for Interdisciplinary Research on AIDS, School of Public Health, Yale University, New Haven, CT, USA.
Amos AprekuDepartment of Biostatistics, T.H. Chan School of Public Health, Harvard University, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-8115-9125
Richard Panix Amoh-OtuYouth Alliance for Health and Human Rights, Kumasi, Ghana.
Edem ZigahBehavioral, Sexual, and Global Health Lab, School of Nursing, University of Rochester, Rochester, NY, USA.
Prince Amu-AduPriorities on Rights and Sexual Health, Accra, Ghana.
Samuel AmuahYouth Alliance for Health and Human Rights, Kumasi, Ghana.ORCID http://orcid.org/0009-0004-6143-7975
Laura NybladeRTI International, Washington, DC, 20005, USA.
Kwasi TorpeyDepartment of Population, Family & Reproductive Health, School of Public Health, University of Ghana, Legon-Accra, Ghana.
LaRon E NelsonCenter for Interdisciplinary Research on AIDS, School of Public Health, Yale University, New Haven, CT, USA.ORCID http://orcid.org/0000-0002-2630-602X

Funding

INTERDISCIPLINARY HIV PREVENTION TRAINING PROGRAMT32MH020031 · NIMH · YALE UNIVERSITY · PI Trace S Kershaw · 1999 to 2026
$12.1M
Multi-Level Intervention Addressing Intersectional Stigma to Improve HIV Testing in MSMR01NR019009 · NINR · YALE UNIVERSITY · PI NELSON, LARON EARNEST, NYBLADE, LAURA · 2019 to 2022
$2.3M
NIH HHS R01NR019009NIH HHS T32 MH020031NIMH NIH HHS T32 MH020031NINR NIH HHS R01 NR019009
6 · The paper itself

Abstract

backgroundGhanaian men who have sex with men (MSM) face significant HIV disparities compared to the general population in Ghana. Pre-exposure prophylaxis (PrEP) is a highly effective tool for HIV prevention. Previous studies on the perspectives of PrEP use among Ghanaian MSM identified high interest in PrEP among this population. However, the knowledge from the previous research, which was the best available evidence at the time, was primarily hypothetical because those data were collected before any real-world implementation of PrEP in Ghana. The analysis aims to identify and understand the factors currently influencing PrEP acceptance.

methodsWe analyzed focus group (n = 8) data with Ghanaian MSM. We transcribed, coded, identified, and analyzed the responses using descriptive thematic analysis.

resultsWe identified two broad themes. Under theme one, which indicated almost universal awareness of PrEP but inaccuracies about PrEP were common, these were the categories: (1) Awareness of PrEP and antiretroviral therapy [ART], (2) confusion between pre-exposure prophylaxis (PrEP) and post-exposure prophylaxis, (3) event-driven perceptions of PrEP usage, (4) Mixed understanding of PrEP: distinguishing PrEP from ART, and (5) advocacy for a comprehensive educational approach. Theme two revealed that PrEP acceptability was influenced by a mix of individual and intrapersonal factors such as (1) hesitancy towards PrEP uptake due to perceived limited benefit, (2) extending HIV, sex, and same-gender sexual relations stigma to PrEP affects uptake, (3) perceived lack of information, concerns about side effects, and cost.

conclusionsTo bridge the gap between awareness, knowledge, and acceptability, HIV prevention programs should address access barriers and incorporate community-derived strategies.

Indexed as

HIV InfectionsHomosexuality, MalePatient Acceptance of Health CarePre-Exposure ProphylaxisSexual and Gender MinoritiesAdultFocus GroupsGhanaHealth Knowledge, Attitudes, PracticeHumansMaleMiddle AgedQualitative ResearchYoung Adult

Identifiers

PMID40611080
PMCPMC12224874

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.