ArticleBMC women's health2025
Effects of benign ovarian cyst volume and laterality on AMH and CA-125 levels.
Article in BMC women's health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07686783 (Ovarian Reserve After Laparoscopic Cystectomy for Endometriotic and Non-Endometriotic Cysts), which is not on this map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Ovarian Reserve After Laparoscopic Cystectomy for Endometriotic and Non-Endometriotic Cysts: A Comparative Prospective Cohort Study
Who cites it
1 citing paper in PubMed.
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study aimed to investigate the effects of cyst volume and bilaterality on serum Anti-Müllerian Hormone (AMH) and CA-125 levels in patients with benign ovarian cysts.
methodsWe retrospectively analyzed 139 patients who underwent cystectomy for benign ovarian cysts. Serum AMH and CA-125 levels were measured preoperatively and at the second post-operative month.
resultsThe mean preoperative AMH level was 3.96 ± 3.48 ng/mL, which significantly decreased to 3.59 ± 3.92 ng/mL postoperatively (p = 0.026), reflecting an average decline of 9.3%. CA-125 levels significantly decreased from 53.1 ± 157.2 to 21.0 ± 18.4 U/mL (p = 0.002). Patients with bilateral cysts had lower AMH levels at the second month (1.67 ± 0.6 vs. 3.80 ± 4.1 ng/mL; p = 0.003) despite similar baseline values.
conclusionBilaterality and cyst volume may negatively affect ovarian reserve postoperatively. The decline in AMH levels, particularly following bilateral ovarian cystectomy, has a significant impact on the ovarian reserve and may have implications for future fertility. Early fertility counselling and ovarian preservation strategies should be considered during surgical planning.
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