Evidence map›Paper›PMID 40611051›Full record

ArticleBMC surgery2025

Laparoscopic versus open resection for unfavorable sites gastric gastrointestinal stromal tumors: a propensity weighted cohort study.

Yang Zong, Yawei Qian, Jianghao Xu, Qingya Li, Linjun Wang, Li Yang, Hao Xu, Jianfeng Gu, Zekuan Xu

Abstract readComparative Study
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Yang Zong *Department of General Surgery, Changshu Hospital Affiliated to Soochow University, Suzhou, Jiangsu, China.
Yawei Qian *Gastric Cancer Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Jianghao XuGastric Cancer Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Qingya LiGastric Cancer Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Linjun WangGastric Cancer Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Li YangGastric Cancer Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Hao XuGastric Cancer Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
Jianfeng GuDepartment of General Surgery, Changshu Hospital Affiliated to Soochow University, Suzhou, Jiangsu, China. jscsgjf@sina.cn.
Zekuan XuGastric Cancer Center, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China. xuzekuan@njmu.edu.cn.

Funding

National Natural Science Foundation of China 81802442National tutorial system training project of Suzhou Qngg2022039the Key discipline project of Changshu CSZDXK202301
6 · The paper itself

Abstract

BACKGROUND AND

objectivesTo compare the efficacy and feasibility of laparoscopic resection with those of open surgery for gastric gastrointestinal stromal tumors (GISTs) in unfavorable locations using the propensity score weighting (PSW) method.

methodsClinicopathological and follow-up data from 170 patients found to have gastric GISTs in unfavorable locations from January 2017 to December 2021 were analyzed retrospectively. Among the 170 patients, 121 underwent laparoscopic surgery, and 49 underwent open surgery. The PSW was used to create balanced cohorts and adjusted for six clinically validated covariates: sex, age, BMI, tumor size, mitotic rate, and recurrence risk.

resultsAfter PSW, 325.2 patients, consisting of 167 laparoscopic (Lap group) and 158.2 open surgery (Open group) patients, were matched. The Lap group had shorter operation times (84.7 ± 37.7 min versus 123.4 ± 46.9 min, P < 0.001) and shorter hospital stays (7.0 [5.0, 8.0] days versus 9.0 [8.0, 11.0] days, P < 0.001) than the Open group. Although the Open group exhibited a numerically higher complication rate (10.24% vs. 4.97%), this difference did not reach statistical significance (P = 0.243). Moreover, no significant differences existed in recurrence-free survival or overall survival.

conclusionsLaparoscopic surgery is safe and feasible for gastric GISTs in unfavorable locations. Compared with open surgery, laparoscopic resection facilitates faster postoperative recovery and has a similar long-term prognosis.

Indexed as

GastrectomyGastrointestinal Stromal TumorsLaparoscopyStomach NeoplasmsAdultAgedFeasibility StudiesFemaleHumansLength of StayMaleMiddle AgedOperative TimePostoperative ComplicationsPropensity ScoreRetrospective StudiesGastrointestinal stromal tumorsLaparoscopySurgical outcomesUnfavorable locations

Identifiers

PMID40611051
PMCPMC12226893

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.