Evidence map›Paper›PMID 40610972›Full record

ArticleBMC public health2025

A survey of availability, price, and affordability of innovative negotiated anticancer medicines: a retrospective study in Jiangsu Province, eastern China.

Rui Ma, Yanyan Liu, Baolong Ding, Yuyang Sun, Hongting Yao, Man Yu, Xiaoye Wang, Lingli Zhang, Xin Li

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. A Delphi Study to Identify Priority Indicators for Formulary Selection of Innovative Anticancer Drugs in China.Health expectations : an international journal of public participation in health care and health policy · 2026
    Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Rui MaSchool of Pharmacy, Nanjing Medical University, Nanjing Jiangsu, 211166, China.
Yanyan LiuNanjing Drum Tower Hospital Clinical College of Nanjing Medical University, Nanjing, China.
Baolong DingSchool of Pharmacy, Nanjing Medical University, Nanjing Jiangsu, 211166, China.
Yuyang SunSchool of Pharmacy, Nanjing Medical University, Nanjing Jiangsu, 211166, China.
Hongting YaoSchool of Pharmacy, Nanjing Medical University, Nanjing Jiangsu, 211166, China.
Man YuSchool of Pharmacy, Nanjing Medical University, Nanjing Jiangsu, 211166, China.
Xiaoye WangSchool of Health Policy and Management, Nanjing Medical University, Nanjing, China.
Lingli ZhangSchool of International Pharmaceutical Business, China Pharmaceutical University, Nanjing, China. zhanglingli@cpu.edu.cn.
Xin LiSchool of Pharmacy, Nanjing Medical University, Nanjing Jiangsu, 211166, China. xinli@njmu.edu.cn.

Funding

National Natural Science Foundation of China,China 72074123National Natural Science Foundation of China,China 72304150
6 · The paper itself

Abstract

backgroundThe emergence of innovative anticancer medicines has revitalized cancer treatment prospects, and improving the accessibility of innovative anticancer medicines is a key goal of national pharmaceutical policies. Despite significant efforts by the National Medical Security Administration to reform the National Reimbursement Drug List (NRDL), concerns regarding the utilization of these newly included anticancer drugs persist. This study aims to assess the accessibility of 23 Innovative Negotiated Anticancer Medicines (INAMs) in Jiangsu Province, a developed region in eastern China.

methodsA retrospective survey was conducted across 319 healthcare institutions in Jiangsu Province, with 285 included for analysis. Data were obtained from procurement records of 23 INAMs. We evaluated the use of these medicines based on three aspects: availability, price measured by the defined daily dose cost (DDDc), and affordability.

results43.5% of the 23 INAMs encountered difficulties in obtaining them, and 30.4% of 23 INAMs were very difficult to obtain. There was a notable disparity in the availability of 23 INAMs between secondary and tertiary healthcare institutions. The median DDDc for Group A and Group C showed a progressive annual reduction. The DDDc of 19 INAMs decreased during the study period, while three drugs remained unchanged, and one drug's DDDc actually increased. Family poverty caused by medicines was more pronounced among rural residents. The affordability of rural patients was significantly lower than that of urban patients (p < 0.05) in 2021 and 2022.

conclusionThe accessibility of INAMs improved from 2020 to 2022. However, the accessibility of INAMs is influenced by various factors, and disparities still exist in access across different healthcare institutions and between urban and rural areas. Effective and sustainable policies need to be developed to ensure equitable access to medicines for all patients.

Indexed as

Antineoplastic AgentsDrug CostsHealth Services AccessibilityChinaHumansNegotiatingRetrospective StudiesAntineoplastic AgentsAccessibilityAffordabilityAvailabilityDefined daily dose costInnovative Negotiated Anticancer Medicines

Identifiers

PMID40610972
PMCPMC12224675

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.