Evidence map›Paper›PMID 40610968›Full record

ArticleBMC public health2025

Quality of life and stigma among persons affected by leprosy or buruli ulcer in Nigeria: a community-based cross-sectional study.

Amaka Esmai-Onyima, Ngozi Ekeke, Ifeyinwa Ezenwosu, Edmund N Ossai, Chinwe Eze, Francis Chinawa, Obiora Iteke, Precious Henry, Charles Nwafor, Ngozi Murphy-Okpala and 4 more

Abstract read
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Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

14 authors.

Amaka Esmai-OnyimaTuberculosis, Leprosy and Buruli ulcer Control Unit, Ogbaru, Anambra State, Nigeria.
Ngozi EkekeRed Aid Nigeria (RAN) Enugu, Enugu, Nigeria.
Ifeyinwa EzenwosuDepartment of Community Medicine, University of Nigeria Teaching Hospital Ituku-Ozalla, Enugu, Nigeria. ifeyinwaezenwosu32@gmail.com.
Edmund N OssaiDepartment of Community Medicine, College of Health Sciences, Ebonyi State University, Abakaliki, Nigeria.
Chinwe EzeRed Aid Nigeria (RAN) Enugu, Enugu, Nigeria.
Francis ChinawaFederal Neuro-Psychiatric Hospital, Enugu, Nigeria.
Obiora ItekeFederal Neuro-Psychiatric Hospital, Enugu, Nigeria.
Precious HenryRed Aid Nigeria (RAN) Enugu, Enugu, Nigeria.
Charles NwaforRed Aid Nigeria (RAN) Enugu, Enugu, Nigeria.
Ngozi Murphy-OkpalaRed Aid Nigeria (RAN) Enugu, Enugu, Nigeria.
Martin NjokuRed Aid Nigeria (RAN) Enugu, Enugu, Nigeria.
Anthony O MekaRed Aid Nigeria (RAN) Enugu, Enugu, Nigeria.
Chukwuma AnyaikeNational Tuberculosis, Leprosy and Buruli ulcer Control Programme (NTBLCP), Abuja, Nigeria.
Joseph N ChukwuGerman Leprosy and TB Relief Association Enugu, Enugu, Nigeria.

Funding

Leprosy Research Initiative 708.20.15/LRI
6 · The paper itself

Abstract

introductionSkin Neglected tropical diseases including leprosy and Buruli ulcer cause aesthetic and functional impairments due to late detection of the diseases. This study assessed the quality of life and stigma among persons affected by leprosy or Buruli ulcer in Nigeria.

methodsThis was a community-based cross-sectional study. It involved 635 persons affected by leprosy or Buruli ulcers who were purposively selected from the endemic local government areas in six Southern States of Nigeria. The SARI Stigma Scale was used to assess stigma while the WHOQOL-BREF questionnaire was used to determine the Quality of life. Chi-square test, Correlation analysis, Mann Whitney U, Kruskal Wallis tests and multivariate analysis using binary logistic regression analysis were used in the study. The level of statistical significance was determined by a p-value of < 0.05.

resultsThe mean age of the respondents was 43.8 ± 17.0years. A higher proportion of the respondents, 78.9% were affected by leprosy. Less than one-third of the respondents, 29.3% had good quality of life. The mean overall stigma score was significantly higher for leprosy patients when compared with BU, (p = 0.042). There was a strong negative correlation between overall stigma and overall quality of life, (n = 635, r=-0.530, p < 0.001). There was a strong positive correlation between overall social support and overall quality of life, (n = 635, r = 0.558, p < 0.001). Predictors of good quality of life included having no formal education, (AOR = 0.4, 95%CI: 0.2-0.7), being unemployed, (AOR = 0.4, 95%CI: 0.2-0.7), having vocational training, (AOR = 2.1, 95%CI: 1.1-4.1), being affected by leprosy, (AOR = 4.3, 95%CI: 2.3-8.1) and having poor social support, (AOR = 0.1, 95%CI: 0.05-0.2).

conclusionThe quality of life of the individuals decreases as the level of stigma increases. Thus, the need to continue community health education campaigns to change the existing stereotypes about the diseases and provide strong social support for the affected individuals.

Indexed as

Buruli UlcerLeprosyQuality of LifeSocial StigmaAdolescentAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedNigeriaSurveys and QuestionnairesYoung AdultLeprosy or buruli ulcerNigeriaQuality of lifeStigma

Identifiers

PMID40610968
PMCPMC12225092

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LicenceCC BY-NC-ND
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.