Evidence map›Paper›PMID 40610954›Full record

ArticleBMC public health2025

High immunisation coverage but sporadic outbreaks of vaccine-preventable diseases: the structural gaps in vaccination uptake in central highlands, Vietnam.

Thanh Ha Nguyen, Thi Phuoc Loan Mai, C Louise Thwaites, Jennifer Ilo Van Nuil, Mary Chambers

Abstract read
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Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Thanh Ha NguyenOxford University Clinical Research Unit, 764 Vo Van Kiet Street, Hochiminh City, Vietnam. hanth@oucru.org.ORCID http://orcid.org/0000-0003-2327-5675
Thi Phuoc Loan MaiCentre for Disease Control Daklak, 72 Le Duan Street, Ban Me Thuot City, Vietnam.
C Louise ThwaitesOxford University Clinical Research Unit, 764 Vo Van Kiet Street, Hochiminh City, Vietnam.ORCID http://orcid.org/0000-0002-4666-9813
Jennifer Ilo Van NuilOxford University Clinical Research Unit, 764 Vo Van Kiet Street, Hochiminh City, Vietnam.ORCID http://orcid.org/0000-0002-5167-5505
Mary ChambersOxford University Clinical Research Unit, 764 Vo Van Kiet Street, Hochiminh City, Vietnam.ORCID http://orcid.org/0000-0003-0535-3895

Funding

Wellcome Trust 228141/Z/23/Z
6 · The paper itself

Abstract

backgroundDespite the successful implementation of the Expanded Programme on Immunization (EPI) for the past three decades, Vietnam has recently witnessed outbreaks of vaccine-preventable diseases, indicating a potential gap in immunisation uptake across population groups. Daklak province is a rural highland area, home to 46 ethnic groups with complicated socio-economic backgrounds. The province reported sporadic outbreaks of vaccine-preventable diseases and low vaccine uptake in some remote low-socioeconomic groups despite a high record of provincial coverage. Within this context, we aim to explore the perspectives and experiences of ethnic minority communities related to EPI vaccination and how socio-economic and contextual factors influence such views and practices in Daklak province.

methodsWe used qualitative data collected between 2018 and 2022 from in-depth interviews, focus group discussions, and participant observation with different stakeholders of the EPI programme. The study took place in nine districts across 25 communes of the province with different socio-economic characteristics and vaccination patterns. We invited mothers who were the primary caregivers taking children to vaccination and healthcare workers who were directly involved in vaccination delivery in the local areas. We incorporated the SAGE's public health framework of the vaccine hesitancy matrix and the anthropological concept of structural vulnerability to discern the structural roots of vaccine attitudes and behaviours of the community.

resultsOverall, the research shows that views and behaviours related to children's vaccination are complicatedly influenced by multi-ecological factors. In particular, we found a critical influence of socioeconomic conditions and social networks on the community's vaccine acceptance and uptake. The community's interaction with the health system and the government through local healthcare workers was also critical in fostering community trust towards vaccines and the EPI programme. In addition, we revealed that the issues with non-compliance to the EPI in the lowest-uptake communities were structurally related to their economic vulnerabilities and social marginalisation.

conclusionsThese findings implicate the need for tailoring public health and socioeconomic interventions to enhance vaccination opportunities in the marginalised groups.

Indexed as

Disease OutbreaksPatient Acceptance of Health CareVaccinationVaccination CoverageVaccine-Preventable DiseasesAdultEthnicityFemaleFocus GroupsHumansImmunization ProgramsInterviews as TopicMaleQualitative ResearchRural PopulationSocioeconomic FactorsSocial marginalisationStructural vulnerabilityVaccine hesitancyVaccine-preventable diseases

Identifiers

PMID40610954
PMCPMC12225764

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.