Evidence map›Paper›PMID 40610951›Full record

ArticleBMC ophthalmology2025

Morphologic features of crystalline lens in cataract patients with different lens sclerosis and axial length.

Rui Qin, Jing Ding, Yiyun Liu, Qianqian Lan, Tong Sun, Linbo Bian, Dehai Liu, Xiaoyu Wang, Jiawei Chen, Zhengze Sun and 1 more

Abstract read
In one paragraph

Article in BMC ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rui QinDepartment of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China.
Jing DingDepartment of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China.
Yiyun LiuDepartment of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China.
Qianqian LanDepartment of Ophthalmology, the People's Hospital of Guangxi Zhuang Autonomous Region, No.6, Taoyuan Road, Guangxi Zhuang Autonomous Region, 530021, Nanning, China. 54283122@qq.com.
Tong SunDepartment of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China.
Linbo BianDepartment of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China.
Dehai LiuDepartment of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China.
Xiaoyu WangDepartment of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China.
Jiawei ChenDepartment of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China.
Zhengze SunDepartment of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China.
Hong QiDepartment of Ophthalmology, Beijing Key Laboratory of Restoration of Damaged Ocular Nerve, Peking University Third Hospital, Beijing, China. doctorqihong@163.com.

Funding

the National Natural Science Foundation of China grants 82171022, 82371026
6 · The paper itself

Abstract

introductionTo investigate morphological features of crystalline lens in cataract patients and examine the association between lens nucleus sclerosis, axial length (AL), and lens morphology.

methodsThis retrospective study consecutive included 285 left cataract eyes at Peking University Third Hospital between July 2022 and June 2023. Lens parameters were measured using CASIA2 and IOL Master 700. Patients were sub-grouped by Emery-Little classification and AL. Statistical and regression analyses were performed.

resultsSevere nuclear sclerosis (Emery-Little grade IV) exhibited smaller back curvature radii (BCR; P = 0.008), lens diameter (P = 0.005), and greater lens decentration (P = 0.012). Long AL eyes (≥ 25.5 mm) showed higher lens decentration (P = 0.026) and lower lens tilt (P < 0.001). BCR strongly correlated with lens diameter (r = 0.904, P < 0.001). Regression identified lens diameter as the primary predictor of BCR (β = 0.758). Compared with the decentration of the lens (R² = 0.045), tilt is easier to predict (R² = 0.125).

conclusionThe degree of lens nucleus sclerosis and axial length may affect the morphologic features of the lens. It may be considered that how the lens morphology with excessive nucleus sclerosis or abnormal axial length impact the efficacy and safety of cataract surgery.

Indexed as

Axial Length, EyeCataractLens, CrystallineLens Nucleus, CrystallineAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedRetrospective StudiesSclerosisAxial lengthCataractLens morphologyNuclear sclerosis

Identifiers

PMID40610951
PMCPMC12224622

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.