SynthesisBMC pregnancy and childbirth2025
Mean Corpuscular Volume (MCV) and Mean Platelet Volume (MPV) as early diagnostic markers for preeclampsia, gestational diabetes, and anemia: a systematic review of clinical evidence and mechanisms.
Synthesis in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Early warning for acute pyelonephritis with sepsis: risk prediction model for patients without renal medullary necrosis lesions.Frontiers in medicine · 2026Article
- Homocysteine combined with multi-index screening for pregnancy complications: a narrative review.Frontiers in endocrinology · 2026Review
- Machine learning-based management of hypertensive disorders in pregnancy: analysis of differences in key risk factors between gestational hypertension and pre-eclampsia and construction of a pre-eclampsia prediction model.European journal of medical research · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThis systematic review (2018-2023) evaluates the diagnostic accuracy of MCV and MPV in pregnancy-related disorders.
objectivesEvaluate diagnostic accuracy of MCV/MPV for pregnancy complications.
methodsPRISMA 2020 review of 36 studies (2018-2023) using automated analyzers.
results- MPV > 10.2 fL predicts preeclampsia (78% sensitivity, AUC 0.81). - MCV < 80 fL indicates iron-deficiency anemia (85% specificity). - MPV > 9.8 fL associates with gestational diabetes (OR 2.3, 95% CI 1.8-3.0). - $0.20/test cost advantage.
conclusionThese low-cost markers could enhance early detection in resource-limited settings. These hematological markers are associated with up to 60% reduction in diagnostic costs when compared to conventional testing methods, making them viable for LMICs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.