Evidence map›Paper›PMID 40610931›Full record

ArticleBMC public health2025

Perception of healthcare professionals about the knowledge of people living with HIV regarding clinical trials for HIV-related cancers.

Jessica Hernández-Marrero, Tanialy Rivera-Santiago, Mariela Bournigal-Feliciano, Vivian Colón-López, Ana I Velázquez, Jorge Salmerón, Joel M Palefsky, Ana P Ortiz, Marievelisse Soto-Salgado

Abstract read
In one paragraph

Article in BMC public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jessica Hernández-MarreroDivision of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico, USA.
Tanialy Rivera-SantiagoDivision of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico, USA.
Mariela Bournigal-FelicianoDivision of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico, USA.
Vivian Colón-LópezDivision of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico, USA.
Ana I VelázquezSchool of Medicine, Division of Hematology/Oncology, University of California San Francisco, San Francisco, CA, USA.
Jorge SalmerónNational Institute of Public Health, Epidemiology, Cuernavaca-Morelos, México and Center for Policy, Population and Health Research, National University, Mexico City, USA.
Joel M PalefskySchool of Medicine, Department of Medicine, University of California San Francisco, San Francisco, CA, USA.
Ana P OrtizDivision of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico, USA.
Marievelisse Soto-SalgadoDivision of Cancer Control and Population Sciences, University of Puerto Rico Comprehensive Cancer Center, San Juan, Puerto Rico, USA. marievelisse.soto1@upr.edu.

Funding

Social determinants of health associated to the cervical cancer-related care across the cancer control continuum among women living with HIV in Puerto RicoP20GM148324 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Vivian Colon · 2023 to 2026
$10.3M
Implementation and evaluation of multiple recruitment research strategies for persons living with HIV in the CAMPO clinical trials in the Puerto Rico siteU54CA242646 · NCI · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI ZHANG, LI · 2019 to 2025
$10.2M
National Cancer Institute of the National Institutes of Health 3U54CA242646-04S2NCI NIH HHS U54 CA242646NIGMS NIH HHS P20 GM148324The Hispanic Alliance for Clinical and Translational Research U54GM133807
6 · The paper itself

Abstract

backgroundAdvances in HIV treatments have prolonged the lifespan of people living with HIV (PLWH), thereby increasing the risk of chronic conditions such as HIV-related cancers. Clinical trials (CT) play an important role in advancing cancer care in PLWH. However, their underrepresentation in CT underscores the need for involvement of healthcare professionals in CT referrals. This study aims to describe healthcare professionals' perception of PLWH understanding of CT for HIV-related cancers.

methodsWe analyzed survey data from a training activity provided to healthcare professionals (n = 82) from HIV-specialized clinics and other healthcare organizations in Puerto Rico to assess healthcare professionals' perception of PLWH knowledge regarding CT for HIV-related cancers.

resultsMost participants were allied healthcare professionals (39.0%) or social services professionals (43.9%), with 70.8% having 1-15 years of experience caring for PLWH. Most participants believed that PLWH had limited knowledge about HIV-related cancers (65.8%) and CT for these cancers (59.8%). Nearly a quarter (23.1%) of healthcare professionals reported hearing expressions of fear regarding CT from PLWH. Conversely, almost half (49.4%) heard positive comments or experiences about participating in CT. The training activity did not include physicians. Perceived barriers for participation of PLWH in CT, according to the healthcare professionals, included fear of the unknown (48.8%), stigma associated with the participation in HIV-related clinical trials (43.9%), and lack of knowledge (42.7%).

conclusionsAccording to healthcare professionals, the participation of PLWH in HIV-related clinical trials could be affected by limited knowledge or awareness about their benefits. Training activities are needed to increase awareness, knowledge and improve the participation of PLWH in HIV-related CT. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Attitude of Health PersonnelClinical Trials as TopicHealth Knowledge, Attitudes, PracticeHealth PersonnelHIV InfectionsNeoplasmsAdultFemaleHumansMaleMiddle AgedPuerto RicoSurveys and QuestionnairesClinical trialsHealthcare providersHIV-related cancersPerception

Identifiers

PMID40610931
PMCPMC12224814

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.