Evidence map›Paper›PMID 40610826›Full record

ArticleSleep & breathing = Schlaf & Atmung2025

Respiratory events and sleep structure of children suffering from congenital central hypoventilation syndrome under assisted ventilation: a cross-sectional descriptive study.

Benjamin Dudoignon, Rodrigue Fikiri Bavurhe, Fatima Benterki, Plamen Bokov, Christophe Delclaux

Abstract read
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In one paragraph

Article in Sleep & breathing = Schlaf & Atmung, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Benjamin DudoignonService de Physiologie Pédiatrique-Centre du Sommeil-CRMR Hypoventilations alvéolaires rares, AP-HP, Hôpital Robert Debré, Paris, 75019, France.
Rodrigue Fikiri BavurheService de Physiologie Pédiatrique-Centre du Sommeil-CRMR Hypoventilations alvéolaires rares, AP-HP, Hôpital Robert Debré, Paris, 75019, France.
Fatima BenterkiService de Physiologie Pédiatrique-Centre du Sommeil-CRMR Hypoventilations alvéolaires rares, AP-HP, Hôpital Robert Debré, Paris, 75019, France.
Plamen BokovService de Physiologie Pédiatrique-Centre du Sommeil-CRMR Hypoventilations alvéolaires rares, Université de Paris-Cité, AP-HP, Hôpital Robert Debré, INSERM NeuroDiderot, AP-HP 48, boulevard Sérurier, Paris, 75019, France.
Christophe DelclauxService de Physiologie Pédiatrique-Centre du Sommeil-CRMR Hypoventilations alvéolaires rares, Université de Paris-Cité, AP-HP, Hôpital Robert Debré, INSERM NeuroDiderot, AP-HP 48, boulevard Sérurier, Paris, 75019, France. christophe.delclaux@aphp.fr.ORCID 0000-0003-2786-0812

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeIt has been reported that children with congenital central hypoventilation syndrome (CCHS) are at risk of sleep disturbances. The objectives of our cross-sectional study were to describe nighttime assisted ventilation in children with CCHS, to assess whether children follow the backup rate of home ventilators, whether sleep structure is altered and whether sleep study and PCO

methodsChildren followed up for annual evaluation, including polysomnography under assisted ventilation (pressure-controlled ventilation with a mask or tracheostomy) with transcutaneous PCO

resultsThirty-eight children (median age [25th; 75th percentiles]: 7.9 years [4.5; 11.1], 18 girls) were enrolled. The observed respiratory rate was significantly lower than the backup rate of the ventilator due to central apneas with upper airway closure under mask ventilation in both NREM and REM sleep during assisted ventilation with mild hypocapnia (nighttime PCO

conclusionWhen the assisted ventilation is set to ensure mild hyperventilation due to the backup respiratory rate, a normal sleep structure is found, and assisted ventilation settings are often modified based on transcutaneous PCO

Indexed as

HypoventilationRespiration, ArtificialSleep Apnea, CentralChildChild, PreschoolCross-Sectional StudiesFemaleHumansMalePolysomnographyAssisted-ventilationCongenital central hypoventilation syndromePolysomnographyTranscutaneous PCO2 measurement

Identifiers

PMID40610826

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.