Evidence map›Paper›PMID 40610806›Full record

ArticleBiotechnology letters2025

High-density heterotrophic cultivation of a cell-wall-deficient Chlamydomonas reinhardtii strain by fed-batch strategy.

Kaidi Zhou, Tao Yu, Minxi Wan, Zhengxu Bao, Wenming Bai, Weiliang Wang, Yuanguang Li

Abstract read
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In one paragraph

Article in Biotechnology letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Kaidi ZhouState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Mail Box 301, Meilong Road 130, Shanghai, 200237, People's Republic of China.
Tao YuState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Mail Box 301, Meilong Road 130, Shanghai, 200237, People's Republic of China.
Minxi WanState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Mail Box 301, Meilong Road 130, Shanghai, 200237, People's Republic of China.
Zhengxu BaoBaoshan Zeyuan Algae Health Technology Co., Ltd., Baoshan, 678208, People's Republic of China.
Wenming BaiBaoshan Zeyuan Algae Health Technology Co., Ltd., Baoshan, 678208, People's Republic of China.
Weiliang WangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Mail Box 301, Meilong Road 130, Shanghai, 200237, People's Republic of China. wlwang@ecust.edu.cn.ORCID http://orcid.org/0009-0007-4273-6373
Yuanguang LiState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Mail Box 301, Meilong Road 130, Shanghai, 200237, People's Republic of China. ygli@ecust.edu.cn.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chlamydomonas reinhardtii CW15, a cell-wall-deficient strain, is a widely used chassis in microalgal genetic engineering. However, its low cell density under autotrophic and mixotrophic cultivation restricts industrial scalability. This study aimed to establish a cost-effective, high-density heterotrophic cultivation process for C. reinhardtii CW15. Initially, an optimized AP medium (Tris-free TAP with K

Indexed as

Batch Cell Culture TechniquesCell WallChlamydomonas reinhardtiiAcetatesAmmoniaBioreactorsCulture MediaFermentationHeterotrophic ProcessesNitrogenAcetatesAmmoniaCulture MediaNitrogenCell-wall-deficient Chlamydomonas reinhardtiiFed-batch cultivationHeterotrophic cultivationProcess optimization

Identifiers

PMID40610806

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.