Evidence map›Paper›PMID 40610668›Full record

ArticleJournal of general internal medicine2025

Unmet Subsistence and Mental Health Needs in Women Experiencing Homelessness: Rethinking Care Models for Improved Outcomes.

Thye Peng Ngo, Torsten B Neilands, Annesa Flentje, Samantha E Dilworth, Elise Riley

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In one paragraph

Article in Journal of general internal medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Thye Peng NgoNational Clinician Scholars Program, Philip R. Lee Institute for Health Policy Studies, University of California, San Francisco, San Francisco, CA, USA. ThyePeng.Ngo@ucsf.edu.ORCID 0000-0002-2246-2455
Torsten B NeilandsUniversity of California, San Francisco, School of Medicine, San Francisco, CA, USA.
Annesa FlentjeStanford University, Stanford Prevention Research Center, School of Medicine, Stanford, CA, USA.
Samantha E DilworthUniversity of California, San Francisco, School of Medicine, San Francisco, CA, USA.
Elise RileyUniversity of California, San Francisco, School of Medicine, San Francisco, CA, USA.

Funding

Impact of Cocaine and Polydrug Use on Cranial Small Vessel DiseaseR01DA037012 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RILEY, ELISE D. · 2014 to 2018
$4.1M
Cocaine use, viral suppression and precursors of stroke in HIV infectionR01DA049648 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RILEY, ELISE D. · 2020 to 2024
$4.0M
Mentoring patient-oriented research on the health consequences of polydrug useK24DA039780 · NIDA · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI RILEY, ELISE D. · 2015 to 2025
$1.9M
NIDA NIH HHS K24 DA039780NIDA NIH HHS R01 DA037012NIDA NIH HHS R01 DA049648
6 · The paper itself

Abstract

backgroundWomen experiencing homelessness or unstable housing (WEH) exhibit disproportionately high rates of depression and anxiety. While existing research links unmet subsistence needs (e.g., housing and food insecurity) to mental health (MH), the intersection of these unmet needs with health and social factors on MH disparities remains underexplored.

objectiveWe examined associations between unmet subsistence needs and MH symptoms among WEH, focusing on interactions with health and social-related factors, including sleep disturbances, pain, and HIV status.

designCross-sectional analysis using baseline data from the PULSE cohort study.

participants245 women recruited from shelters, free meal programs, and street encampments. MAIN MEASURES: We measured anxiety with the Generalized Anxiety Disorder 7-item (GAD-7) and depression with the Patient Health Questionnaire (PHQ-9). Unmet subsistence needs included insufficient access to shelter, food, clothing, and hygiene resources. KEY

resultsNearly half (49%) of WEH had moderate to severe depression, 36% had moderate to severe anxiety, and nearly 40% had at least one unmet subsistence need. WEH with ≥ 2 unmet needs had almost four times the odds of depression (AOR = 3.96, 95% CI = 1.84, 8.51) and nearly three times the odds of anxiety (AOR = 2.83, 95% CI = 1.39, 5.77) than those without unmet needs. Sleep disturbance and pain were also associated with higher odds of depression (AOR = 4.46, 95% CI = 2.28, 8.71; AOR = 7.01, 95% CI: 3.40, 14.44) and anxiety (AOR = 5.01, 95% CI = 2.70, 9.31; AOR = 3.60, 95% CI = 1.73, 7.50). HIV modified the effect of unmet needs, with seven times higher odds of anxiety among women with HIV who also had ≥ 2 unmet needs (AOR = 7.11, 95% CI = 1.06, 48.00).

conclusionUnmet subsistence needs, sleep disturbances, and pain contribute to depression and anxiety among WEH, particularly those living with HIV. Low-barrier care models that address social needs alongside medical care may improve MH outcomes in WEH.

Indexed as

Health Services Needs and DemandIll-Housed PersonsMental HealthAdultAnxietyCohort StudiesCross-Sectional StudiesDepressionFemaleHumansMiddle Agedmental healthunmet subsistence needswomen experiencing homelessness

Identifiers

PMID40610668
PMCPMC12508409

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.