The network approach to psychopathology: investigating inter-individual variability and the association with clinical relapse in psychosis.

George Gillett, Dan W Joyce, Cedric E Ginestet, James H MacCabe, Nicholas Meyer

Abstract read

In one paragraph

Article in Schizophrenia (Heidelberg, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it

0cells of the map it votes in

0citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

George GillettCentre for Family Research, Department of Psychology, University of Cambridge, Free School Lane, Cambridge, UK. gg555@cam.ac.uk.ORCID http://orcid.org/0000-0002-0270-9369

Dan W JoyceDepartment of Primary Care and Mental Health, University of Liverpool, Liverpool, UK.ORCID http://orcid.org/0000-0002-9433-5340

Cedric E GinestetDepartment of Biostatistics and Health Informatics, King's College London, London, UK.

James H MacCabeDepartment of Psychosis Studies, Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.ORCID http://orcid.org/0000-0002-6754-1018

Nicholas MeyerDepartment of Psychosis Studies, Institute of Psychology, Psychiatry and Neuroscience, King's College London, London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent years have seen a proliferation of interest in psychological networks, which conceptualise psychopathology as networks of inter-connected, mutually reinforcing symptoms. It has been hypothesised that the topological structure of such networks is associated with clinical presentation. Analysing data from a longitudinal study of participants diagnosed with psychosis, we identify substantial inter-individual variability in network structure, problematising causal inference from cross-sectional networks. Additionally, we do not find strong evidence for an association between network structure and clinical relapse.

Identifiers

PMID40610452

DOI10.1038/s41537-025-00636-8

PMCPMC12229628

What OpenQuestion holds

Textmetadata

LicenceCC BY

Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.