Evidence map›Paper›PMID 40610388›Full record

SynthesisPsyCh journal2025

Effectiveness of Cognitive Behavioral Therapy in Reducing Suicidal Ideation and Influential Factors in Patients With Major Depressive Disorder: A Systematic Review and Meta-Analysis.

Mengzhen Zhao, Peng Wang

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in PsyCh journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Mengzhen ZhaoSchool of Sociology, Beijing Normal University, Beijing, China.
Peng WangDepartment of Language, Literature and Communication, Faculty of Social Sciences and Humanities, Vrije Universiteit Amsterdam, Amsterdam, the Netherlands.ORCID https://orcid.org/0000-0002-3475-1561

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To evaluate the effectiveness of cognitive behavioral therapy (CBT) interventions in reducing suicidal ideation among patients with depression, and to identify factors that moderate treatment outcomes, a systematic review and meta-analysis was conducted searching seven major biomedical databases (CNKI, China Wanfang Database, Cochrane Library, PubMed, Web of Science, Embase, and Sinomed) from inception to November 8, 2023. Randomized controlled trials examining CBT interventions for suicidal ideation in depressed patients were included. Fourteen studies (1256 patients) met inclusion criteria. CBT demonstrated a moderate effect in reducing suicidal ideation compared to control conditions (Hedges' g = -0.47 (95% CI [-0.73, -0.22]), p < 0.01). Significant moderators included intervention mode (Q = 8.33, p < 0.05), suicidal ideation measure (Q = 17.98, p < 0.001), intervention duration (Q = 9.55, p < 0.05), and CBT follow-up interval (Q = 6.66, p < 0.05). Age, intervention cycles, frequency, and intervention form did not significantly moderate outcomes. No publication bias was detected, and the overall quality of evidence was moderate. CBT is effective in reducing suicidal ideation among patients with depression. Factors associated with greater effectiveness include combining CBT with drug, targeting older adults, using specific suicidal ideation measures (e.g., C-SSRS, SIOSS), interventions lasting 0-12 weeks with more than once a week, more than an hour per session, and short-term follow-up. Group therapy formats may also enhance outcomes. Future randomized trials should further examine these factors and assess impacts on suicidal behaviors in addition to ideation.

Indexed as

Cognitive Behavioral TherapyMajor Depressive DisorderSuicidal IdeationHumansRandomized Controlled Trials as TopicTreatment Outcomecognitive behavioral therapydepressionsuicidal ideation

Identifiers

PMID40610388
PMCPMC12520839

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.