Evidence map›Paper›PMID 40610236›Full record

ArticleAJNR. American journal of neuroradiology2025

Prevalence of Endolymphatic Hydrops Herniation into the Semicircular Canals in Primary Hydropic Ear Disease: Correlation with Clinical and Radiologic Parameters.

Lisa M H de Pont, Berit M Verbist, Mark A van Buchem, Claire Bommeljé, Henk M Blom, Sebastiaan Hammer

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Article in AJNR. American journal of neuroradiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Lisa M H de PontFrom the Department of Radiology (L.M.H.d.P., S.H.), Haga Hospital, The Hague, The Netherlands l.depont@hagaziekenhuis.nl.ORCID https://orcid.org/0000-0001-7640-7630
Berit M VerbistDepartment of Radiology (L.M.H.d.P., B.M.V., M.A.v.B.), Leiden University Medical Center, Leiden, The Netherlands.ORCID https://orcid.org/0000-0002-1010-2583
Mark A van BuchemDepartment of Radiology (L.M.H.d.P., B.M.V., M.A.v.B.), Leiden University Medical Center, Leiden, The Netherlands.ORCID https://orcid.org/0000-0003-1881-1998
Claire BommeljéDepartment of Otorhinolaryngology (C.B., H.M.B.), Haga Hospital, The Hague, The Netherlands.ORCID https://orcid.org/0000-0001-7227-6629
Henk M BlomDepartment of Otorhinolaryngology (C.B., H.M.B.), Haga Hospital, The Hague, The Netherlands.ORCID https://orcid.org/0000-0002-6075-9647
Sebastiaan HammerFrom the Department of Radiology (L.M.H.d.P., S.H.), Haga Hospital, The Hague, The Netherlands.ORCID https://orcid.org/0000-0002-1576-1190

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeDelayed postcontrast FLAIR MRI can be used to visualize endolymphatic hydrops (EH) and their herniation into the semicircular canals (SCCs), which has been linked to impaired caloric function. However, the prevalence and anatomic distribution of EH herniation and its clinical relevance remains unclear. The purpose of this study is to investigate the frequency and localization of EH herniation into the SCCs in patients with primary hydropic ear disease (HED) and to correlate these findings with clinical parameters. MATERIALS AND

methodsThis was a retrospective study evaluating 409 patients with MRI-confirmed primary HED for the presence and anatomic location of EH herniation into the SCCs. Findings were correlated with the severity of cochleovestibular EH, vertiginous symptoms, audiometric data, and caloric test results.

resultsEH herniation into the SCCs was identified in 172 (42%) of patients with primary HED. The most frequent site of herniation was the nonampullated limb of the horizontal SCC (hSCC) (

conclusionsEH herniation predominantly occurs in the nonampullated limb of the hSCC and is associated with prolonged disease duration, greater severity of EH, and a more pronounced impairment of caloric function.

Indexed as

Endolymphatic HydropsMagnetic Resonance ImagingSemicircular CanalsAdolescentAdultAgedAged, 80 and overComorbidityFemaleHumansMaleMiddle AgedPrevalenceRetrospective StudiesYoung Adult

Identifiers

PMID40610236
PMCPMC12453509

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