ArticleNursing open2025
On Patient Quality of Life: Impacts of Knee Osteoarthritis on Pain, Anxiety, Depression, Fatigue and Sleep Disorders.
Article in Nursing open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Predicting sleep disorder trajectories in older patients with chronic pain: an explainable machine learning approach.BMC psychiatry · 2026Article
- Pain, post-traumatic stress, and sleep disturbance in older adults with knee osteoarthritis: a path analysis of the mediating effect of depression and social support.BMC geriatrics · 2026Article
- Tracking global quality of life trajectories in knee osteoarthritis: a population-based long-term analysis.Therapeutic advances in musculoskeletal disease · 2026Article
- Psychological stress and gut microbiota regulation of osteoarthritis progression: mechanisms and therapeutic strategies.Frontiers in microbiology · 2026Review
- Threshold Effect of Anxiety in the Comorbidity of Depression and Chronic Pain: A Cross-Sectional Study Based on Pain Sensitivity.Neuropsychiatric disease and treatment · 2026Article
- On Patient Quality of Life: Impacts of Knee Osteoarthritis on Pain, Anxiety, Depression, Fatigue and Sleep Disorders.Nursing open · 2025Article
- Reduced Risk of Sleep Disturbance and Obstructive Sleep Apnea Following Joint Replacement in Osteoarthritis Patients.International journal of medical sciences · 2025Article
- Ecological momentary assessment for symptom monitoring among people with knee osteoarthritis: A scoping review.Digital healthReview
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimPatients repeatedly experiencing a sustained disease course, recurrent chronic pain, and serious sleep disorder will weaken their physical resistance and self-care ability. Further evidence on patients with knee osteoarthritis (KOA) and related latent classes (LCs) of symptom clusters is needed in order to clarify its significance for symptom management and quality of life (QoL) enhancement.
designThis study aimed to generate evidence on differences in symptoms experienced by patients with knee osteoarthritis, identify related LCs, and explore the differences of each LC by demographic, disease, individual characteristics, and QoL.
methodsA convenience sample of 230 participants with knee osteoarthritis was surveyed. Sociodemographic and symptom questionnaires were collected. The analysis focused on the influencing factors that are associated with LC, intergroup differences, and associated QoL impacts.
resultsA total of 230 participants with knee osteoarthritis completed the survey, average age was 64.54 ± 7.59. Three LCs were associated with knee osteoarthritis: LC1 (low symptom class), LC2 (high psychological disorder class) and LC3 (high fatigue with sleep disorder class), accounting for 56%, 24% and 20% respectively. Compared to LC1, LC2 was related to poor economic status, higher imaging grade and lower self-efficacy. Notably, being older, being less educated, higher occurrence of chronic diseases, experiencing negative life events and having lower self-efficacy rose in LC3. PATIENT OR PUBLIC CONTRIBUTION: The study identified LCs according to pain, anxiety, depression, fatigue and sleep disorder symptoms among patients with KOA, providing a foundation for further determining whether the clusters vary over time or along disease and treatment trajectory and what their possible synergistic effects are on KOA and associated QoL.
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