Evidence map›Paper›PMID 40609970›Full record

ArticleEnvironmental science & technology2025

Integrating Contaminant Source Indicators, Water Quality Measures, and Ecotoxicity to Characterize Contaminant Mixtures and Per- and Polyfluoroalkyl Substance (PFAS) Variability in an Urban Watershed.

Jonathan R Behrens, Abigail S Joyce, P Lee Ferguson, Dana W Kolpin, Nishad Jayasundara, Nadia Barbo, Emily S Bernhardt

Abstract read
In one paragraph

Article in Environmental science & technology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Jonathan R BehrensDepartment of Biology, Duke University, Durham, North Carolina 27708, United States.ORCID 0000-0002-9473-7139
Abigail S JoyceDepartment of Civil and Environmental Engineering, Duke University, Durham, North Carolina 27708, United States.ORCID 0000-0002-5322-3035
P Lee FergusonDepartment of Civil and Environmental Engineering, Duke University, Durham, North Carolina 27708, United States.ORCID 0000-0002-8367-7521
Dana W KolpinU.S. Geological Survey, Iowa City, Iowa 52244, United States.ORCID 0000-0002-3529-6505
Nishad JayasundaraNicholas School of the Environment, Duke University, Durham, North Carolina 27708, United States.ORCID 0000-0003-2485-6893
Nadia BarboNicholas School of the Environment, Duke University, Durham, North Carolina 27708, United States.ORCID 0009-0002-8534-7769
Emily S BernhardtDepartment of Biology, Duke University, Durham, North Carolina 27708, United States.ORCID 0000-0003-3031-621X

Funding

Zebrafish as a Detector of Organophosphate ExposureP42ES010356 · NIEHS · DUKE UNIVERSITY · PI AMY H HERRING · 2000 to 2026
$56.2M
NIEHS NIH HHS P42 ES010356
6 · The paper itself

Abstract

Thousands of chemical contaminants threaten watersheds but are time and cost prohibitive to monitor. Identifying their sources, transport, and ecological risk is limited in heterogeneous urban watersheds. We present an integrative watershed approach using source-specific indicator compounds, common water quality measures, and ecotoxicity assays to examine the distribution of contaminant mixtures in an urbanized watershed. Indicator compound concentrations were temporally and spatially distributed for treated/untreated sewage (sucralose, artificial sweetener), road runoff (diphenyl-guanidine [DPG] and 6PPD-quinone [6PPD-Q], automobile tire additives), and lawncare runoff (aminomethanephosphonic acid (AMPA), major degradant of the herbicide glyphosate). Sucralose was predominately sourced from treated wastewater; measurable concentrations in tributaries indicated raw sewage inputs. DPG and 6PPD-Q concentrations correlated to road density during base flow and were elevated during stormflow. AMPA was measurable spring through fall, especially where lawns were dense. When specific sources dominated flow, water quality measures correlated with wastewater (sulfate, potassium, chloride, and sodium) and road runoff (chromium and lead) indicators. The limited behavioral toxicity observed in exposed zebrafish (

Indexed as

Water Pollutants, ChemicalWater QualityAnimalsEnvironmental MonitoringWastewaterZebrafishWastewaterWater Pollutants, Chemicalmonitoringpollutantrunoffstormwatersurface waterwastewater

Identifiers

PMID40609970
PMCPMC12269787

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.