Evidence map›Paper›PMID 40609511›Full record

ArticleEnvironment international2025

Guidance on minimum information requirements (MIR) from designing to reporting human biomonitoring (HBM).

Maryam Zare Jeddi, Karen S Galea, Jillian Ashley-Martin, Julianne Nassif, Tyler Pollock, Devika Poddalgoda, Konstantinos M Kasiotis, Kyriaki Machera, Holger M Koch, Marta Esteban López and 71 more

Abstract read
In one paragraph

Article in Environment international, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

81 authors.

Maryam Zare JeddiShell Global Solutions Internationals BV, the Netherlands; Life Science Intelligence Consulting, the Netherlands. Electronic address: Maryam.zarejeddi@shell.com.
Karen S GaleaInstitute of Occupational Medicine (IOM), Edinburgh, UK.
Jillian Ashley-MartinEnvironmental Health Science and Research Bureau, Health Canada, 269 Laurier Ave W, Ottawa, ON K1A 0K9, Canada.
Julianne NassifAssociation of Public Health Laboratories, Bethesda, MD, the United States of America.
Tyler PollockEnvironmental Health Science and Research Bureau, Health Canada, 269 Laurier Ave W, Ottawa, ON K1A 0K9, Canada.
Devika PoddalgodaExisting Substances Risk Assessment Bureau, Health Canada, 269 Laurier Ave W, Ottawa, ON K1A 0K9, Canada.
Konstantinos M KasiotisBenaki Phytopathological Institute, Laboratory of Pesticides' Toxicology, 8, Stephanou Delta Street, 14561 Kifissia, Athens, Greece.
Kyriaki MacheraBenaki Phytopathological Institute, Laboratory of Pesticides' Toxicology, 8, Stephanou Delta Street, 14561 Kifissia, Athens, Greece.
Holger M KochInstitute for Prevention and Occupational Medicine of the German Social Accident Insurance, Institute of the Ruhr University Bochum (IPA), Germany.
Marta Esteban LópezNational Center for Environmental Health, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.
Ming Kei ChungJC School of Public Health and Primary Care, The Chinese University of Hong Kong, Hong Kong, PR China; Institute of Environment, Energy and Sustainability, The Chinese University of Hong Kong, Hong Kong, PR China; Li Ka Shing Institute of Health Sciences, The Chinese University of Hong Kong, Hong Kong, PR China.
Jihyon KilEnvironmental Health Research Division, National Institute of Environmental Research, Ministry of Environment, Incheon 22689, Republic of Korea.
Kate JonesHealth and Safety Executive, Buxton SK17 9JN, UK.
Adrian CovaciToxicological Center, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk, Belgium.
Yu Ait BamaiCenter for Environmental and Health Sciences, Hokkaido University, Kita 12, Nishi 7, Kita-ku, Sapporo, Japan.
Mariana F FernandezUniversity of Granada, Spain, Instituto de Investigación Biosanitaria (ibs.GRANADA), Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Spain.
Robert Pasanen KaseState Secretariat for Economic Affairs SECO, CH, Switzerland.
Henriqueta LouroNational Institute of Health Doutor Ricardo Jorge, Department of Human Genetics, Lisbon and ToxOmics - Centre for Toxicogenomics and Human Health, NOVA Medical School, Universidade NOVA de Lisboa, Lisbon, Portugal.
Maria J SilvaNational Institute of Health Doutor Ricardo Jorge, Department of Human Genetics, Lisbon and ToxOmics - Centre for Toxicogenomics and Human Health, NOVA Medical School, Universidade NOVA de Lisboa, Lisbon, Portugal.
Tiina SantonenFinnish Institute of Occupational Health, Helsinki, Finland.
Andromachi KatsonouriState General Laboratory, Ministry of Health, PO Box 28648 Nicosia, Cyprus.
Argelia CastañoNational Center for Environmental Health, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain; Comprehensive Health Research Centre (CHRC), NOVA Medical School, Universidade NOVA de Lisboa, Portugal.
Lesliam Quirós-AlcaláDepartment of Environmental Health and Engineering, Johns Hopkins University Bloomberg School of Public Health, Baltimore, MD, the United States of America.
Elizabeth Ziying LinEnvironmental Health Sciences, Yale School of Public Health, New Haven, CT 06510, the United States of America.
Krystal PollittEnvironmental Health Sciences, Yale School of Public Health, New Haven, CT 06510, the United States of America.
Ana VirgolinoEnviHeB Lab, Instituto de Saúde Ambiental, Faculdade de Medicina da Universidade de Lisboa, Lisboa, Portugal.
Paul T J ScheepersRadboud Institute for Biological and Environmental Sciences, Radboud University, Nijmegen, the Netherlands.
Lisa Jo MelnykUS EPA Office of Research and Development, Center for Public Health and Environmental Assessment, Cincinnati, the United States of America.
Vicente MustielesUniversity of Granada, Spain, Instituto de Investigación Biosanitaria (ibs.GRANADA), Consortium for Biomedical Research in Epidemiology and Public Health (CIBERESP), Spain.
Ana Isabel Cañas PortillaNational Center for Environmental Health, Instituto de Salud Carlos III, 28220 Majadahonda, Madrid, Spain.
Susana ViegasNOVA National School of Public Health, Public Health Research Centre, Comprehensive Health Research Center, CHRC, REAL, CCAL, NOVA University Lisbon, Lisbon, Portugal.
Natalie von GoetzFederal Office of Public Health, Berne, Switzerland.
Ovnair SepaiGeneral Toxicology and Biomonitoring, Radiation Chemical Climate and Environment Division, UK Health Security Agency, UK.
Emily BirdGeneral Toxicology and Biomonitoring, Radiation Chemical Climate and Environment Division, UK Health Security Agency, UK.
Thomas GöenFriedrich-Alexander-Universität Erlangen-Nürnberg, Institute and Outpatient Clinic of Occupational, Social and Environmental Medicine, Erlangen, Germany.
Silvia FustinoniDepartment of Clinical Sciences and Community Health, University of Milan, Milan, Italy.
Manosij GhoshDepartment of Public Health and Primary Care, Environment and Health Unit, KU Leuven, Leuven, Belgium.
Hubert DirvenDept of Chemical Toxicology, Division of Climate and Environmental Health, Norwegian Institute of Public Health, Oslo, Norway.
Jung-Hwan KwonDivision of Environmental Science and Ecological Engineering, Korea University, Republic of Korea.
Courtney CarignanDepartment of Food Science and Human Nutrition, Department of Pharmacology and Toxicology, Michigan State University, East Lansing, US, the United States of America.
Yuki MizunoDepartment of Environmental Health Sciences, Mailman School of Public Health, Columbia University, the United States of America.
Yuki ItoDepartment of Occupational and Environmental Health, Nagoya City University Graduate School of Medical Science, Nagoya, Japan.
Yankai XiaKey Laboratory of Modern Toxicology of Ministry of Education, School of Public Health, Nanjing Medical University, Nanjing 211166, PR China.
Shoji F NakayamaExposure Dynamics Research Section, Health and Environmental Risk Division, National Institute for Environmental Studies, 16-2 Onogawa, Tsukuba, Ibaraki 305-8506, Japan.
Konstantinos C MakrisCyprus International Institute for Environmental and Public Health, School of Health Sciences, Cyprus University of Technology, Irinis 95, 3041 Limassol, Cyprus.
Patrick J ParsonsDivision of Environmental Health Sciences, Wadsworth Center, New York State Department of Health, Albany, NY, the United States of America; Department of Environmental Health Sciences, College of Integrated Health Sciences, University at Albany, Albany, NY, the United States of America.
Melissa GonzalesTulane School of Public Health and Tropical Medicine - Environmental Health Sciences, Tidewater Building, 1440 Canal Street, #8360, New Orleans, LA 70112, the United States of America.
Michael BaderBASF SE, Corporate Health Management, Ludwigshafen, Germany.
Maria DusinskaThe Health Effects Laboratory, Department of Environmental Chemistry and Health Effects, Climate and Environmental Research Institute NILU, Kjeller, Norway.
Aziza MenouniDepartment of Public Health and Primary Care, Environment and Health Unit, KU Leuven, Leuven, Belgium.
Radu Corneliu DucaDepartment of Public Health and Primary Care, Environment and Health Unit, KU Leuven, Leuven, Belgium; Department of Health Protection, Laboratoire National de Santé, 1, Rue Louis Rech, L-3555 Dudelange, Luxembourg.
Kaoutar ChbihiDepartment of Public Health and Primary Care, Environment and Health Unit, KU Leuven, Leuven, Belgium; Human Epidemiology and Environmental Health Research Team, Faculty of Sciences, Moulay Ismail University of Meknes, Meknes 50000, Morocco.
Samir El JaafariHuman Epidemiology and Environmental Health Research Team, Faculty of Sciences, Moulay Ismail University of Meknes, Meknes 50000, Morocco.
Lode GodderisDepartment of Public Health and Primary Care, Environment and Health Unit, KU Leuven, Leuven, Belgium.
An van NieuwenhuyseDepartment of Public Health and Primary Care, Environment and Health Unit, KU Leuven, Leuven, Belgium; Department of Health Protection, Laboratoire National de Santé, 1, Rue Louis Rech, L-3555 Dudelange, Luxembourg.
Asif QureshiDepartment of Climate Change & Department of Civil Engineering, IIT Hyderabad, Sangareddy 502285, India.
Imran AliSwedish Chemicals Agency, Health Assessment/Authorisation, Stockholm, Sweden.
Carla Costa TrindadeDepartment of Environmental Health, National Institute of Health, Porto, Portugal and EPIUnit-Instituto de Saúde Pública da Universidade do Porto, Porto, Portugal.
Joao Paulo TeixeiraDepartment of Environmental Health, National Institute of Health, Porto, Portugal and EPIUnit-Instituto de Saúde Pública da Universidade do Porto, Porto, Portugal.
Alena BartonovaDepartment of Urban Environment and Industry, Climate and Environmental Research Institute NILU, Kjeller, Norway.
Giovanna TranfoItalian Institute Against Accidents at Work (INAIL) Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, Italy.
Karine AudouzeUniversité Paris Cité. Inserm U1124, Paris, France.
Steven VerpaeleNiPERA Inc., 2525 Meridian Parkway, Suite 240, Durham, NC 27713, the United States of America; Belgian Center for Occupational Hygiene (BeCOH), Leuven, Belgium.
Judy LaKindLaKind Associates, LLC, Department of Epidemiology and Public Health, University of Maryland School of Medicine, the United States of America.
Hans MolWageningen Food Safety Research (WFSR), Wageningen University & Research, Wageningen, the Netherlands.
Jos BessemsVITO Environmental Intelligence, Flemish Institute for Technologcal Research (VITO), Mol, Belgium.
Barbara MagagnaGO FAIR Foundation, Leiden, NL, the Netherlands.
Maisarah Nasution WarasDepartment of Toxicology, Advanced Medical and Dental Institute, Universiti Sains Malaysia, 13200 Kepala Batas, P. Pinang, Malaysia.
Alison ConnollyUCD Centre for Safety & Health at Work, School of Public Health, Physiotherapy, and Sports Science, University College Dublin, Dublin, Ireland.
Marc NascarellaMassachusetts College of Pharmacy and Health Sciences University, Boston, MA, the United States of America.
Wonho YangDepartment of Health & Safety, Daegu Catholic University, South Korea.
Po-Chin HuangNational Institute of Environmental Health Sciences, National Health Research Institutes, Miaoli 35053, Taiwan.
Jueun LeeEnvironmental Health Research Division, National Institute of Environmental Research, Ministry of Environment, Incheon 22689, Republic of Korea.
Henri HeussenStoffenmanager®, Van Heuven Goedhartlaan 121, 1181 KK Amstelveen, the Netherlands.
Ozlem GokselEge University, Faculty of Medicine. Laboratory of Occupational/Environmental Respiratory Diseases and Asthma. EgeSAM (Ege University Translational Pulmonary Research Center), 35100 Izmir, Turkiye.
Masud YunesianDepartment of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
Leo W Y YeungMan-Technology-Environment (MTM) Research Centre, School of Science and Technology, Örebro University, 701 82 Örebro, Sweden.
Gustavo SouzaDepartment of Environmental and Occupational Health Surveillance, Secretariat of Health and Environment Surveillance, Ministry of Health, Brazil.
Ana Maria VekicDepartment of Environmental and Occupational Health Surveillance, Secretariat of Health and Environment Surveillance, Ministry of Health, Brazil.
Erin N HaynesDepartment of Epidemiology and Environmental Health, College of Public Health, University of Kentucky, the United States of America.
Nancy B HopfUnisanté, University Center for Primary Care and Public Health & University of Lausanne, Lausanne, Switzerland. Electronic address: nancy.hopf@unisante.ch.

Funding

Intramural EPA EPA999999
6 · The paper itself

Abstract

Human biomonitoring (HBM) provides an integrated chemical exposures assessment considering all routes and sources of exposure. The accurate interpretation and comparability of biomarkers of exposure and effect depend on harmonized, quality-assured sampling, processing, and analysis. Currently, the lack of broadly accepted guidance on minimum information required for collecting and reporting HBM data, hinders comparability between studies. Furthermore, it prevents HBM from reaching its full potential as a reliable approach for assessing and managing the risks of human exposure to chemicals. The European Chapter of the International Society of Exposure Science HBM Working Group (ISES Europe HBM working group) has established a global human biomonitoring community network (HBM Global Network) to develop a guidance to define the minimum information to be collected and reported in HBM, called the "Minimum Information Requirements for Human Biomonitoring (MIR-HBM)". This work builds on previous efforts to harmonize HBM worldwide. The MIR-HBM guidance covers all phases of HBM from the design phase to the effective communication of results. By carefully defining MIR for all phases, researchers and health professionals can make their HBM studies and programs are robust, reproducible, and meaningful. Acceptance and implementation of MIR-HBM Guidelines in both the general population and occupational fields would improve the interpretability and regulatory utility of HBM data. While implementation challenges remain-such as varying local capacities, and ethical and legal differences at the national levels, this initiative represents an important step toward harmonizing HBM practice and supports an ongoing dialogue among policymakers, legal experts, and scientists to effectively address these challenges. Leveraging the data and insights from HBM, policymakers can develop more effective strategies to protect public health and ensure safer working environments.

Indexed as

Biological MonitoringEnvironmental ExposureEnvironmental MonitoringGuidelines as TopicHumansChemical monitoringContextual informationExposomeFAIRHarmonizationMetadata requirements

Identifiers

PMID40609511
PMCPMC12621227

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.