Evidence map›Paper›PMID 40608572›Full record

ArticleRevista brasileira de epidemiologia = Brazilian journal of epidemiology2025

Analysis of mortality by cardiovascular disease subgroups in Brazil before and during the COVID-19 pandemic (2000-2022) by sex and age group.

Cicero Emanoel Alves Leite, Raphael Mendonça Guimarães, Andréa Sobral

Abstract read
In one paragraph

Article in Revista brasileira de epidemiologia = Brazilian journal of epidemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

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0cells of the map it votes in
2citing papers in PubMed
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1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

3 authors.

Cicero Emanoel Alves LeiteFundação Oswaldo Cruz, Sérgio Arouca National School of Public Health, Postgraduate Program in Public Health and Environment - Rio de Janeiro (RJ), Brazil.ORCID http://orcid.org/0000-0001-8981-493X
Raphael Mendonça GuimarãesFundação Oswaldo Cruz, Sérgio Arouca National School of Public Health, Department of Social Sciences - Rio de Janeiro (RJ), Brazil.ORCID http://orcid.org/0000-0003-1225-6719
Andréa SobralFundação Oswaldo Cruz, Sérgio Arouca National School of Public Health, Department of Endemic Diseases Samuel Pessoa - Rio de Janeiro (RJ), Brazil.ORCID http://orcid.org/0000-0003-0552-771X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo analyze the effect of the COVID-19 pandemic on mortality by cardiovascular disease (CVD) subgroups in Brazil, considering sex and age group.

methodsEcological time-series study with secondary data from the Mortality Information System for the period 2000-2022. Age-adjusted mortality rates per 100,000 inhabitants were calculated and joinpoint regression models were used to estimate rate trends.

resultsMortality from CVD in Brazil between 2000 and 2022 showed a decrease in ischemic heart disease (IHD) and cerebrovascular disease (CBVD), while other CVD showed an unstable behavior, increasing after 2020. The reduction in IHD was more pronounced until 2020, decelerating thereafter. CBVD continued to decline but at a slower pace. Other CVD, after a downward trend, showed a significant increase (+3.8% per year), possibly because of the pandemic. Women had a greater reduction in mortality, especially due to IHD. Intermediate age groups (40-59 years) showed a decrease until 2020 but recorded increases after this period, reinforcing the impact of the pandemic. In 2021, all subgroups showed excess mortality: 8% for CBVD and IHD, and 15% for other CVD. In 2022, this pattern intensified, with values of 16% (CBVD), 18% (IHD) and 23% (other CVD).

conclusionThe COVID-19 pandemic significantly impacted CVD mortality in Brazil, changing trends according to age group, sex and disease subgroup. The study points to an inflection in mortality rates during the pandemic, highlighting the need for further investigations to understand the mechanisms involved.

Indexed as

Cardiovascular DiseasesCOVID-19AdolescentAdultAgedAged, 80 and overAge DistributionAge FactorsBrazilFemaleHumansMaleMiddle AgedPandemicsSex DistributionSex Factors

Identifiers

PMID40608572
PMCPMC12204235

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.