Evidence map›Paper›PMID 40608278›Full record

ReviewJournal of echocardiography2025

Clinical utility of the left atrial strain analysis.

Katsuji Inoue, Masaru Obokata

Abstract readReview
In one paragraph

Review in Journal of echocardiography, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
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  14. Preventing atrial fibrillation with SGLT2 inhibitors: time, sex, and substrate.European heart journal. Cardiovascular pharmacotherapy · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Katsuji InoueDepartment of Community Emergency Medicine, Ehime University Graduate School of Medicine, Ohhira 1-638, Yawatahama, Ehime, 796-8502, Japan. inoue.katsuji.my@ehime-u.ac.jp.ORCID http://orcid.org/0000-0001-7922-0521
Masaru ObokataDepartment of Cardiovascular Medicine, Gunma University Graduate School of Medicine, Maebashi, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The importance of left atrial (LA) function is recognized, especially when left ventricular function fails or atrial fibrillation occurs and heart failure (HF) develops. A compensatory mechanism of LA function unremittingly operates to maintain cardiac performance and prevent the occurrence of HF. LA function consists of three components: booster pump, reservoir, and conduit function. Echocardiography enables assessment of these components of LA function by LA volumetric changes in one cardiac cycle. Currently, LA strain has emerged as a valuable diagnostic and prognostic tool in patients with various cardiovascular diseases. An aging society is confronted with an issue of public health due to an increased number of patients with heart failure with preserved ejection fraction (HFpEF). Because effective medical and interventional approaches for patients with HFpEF are limited, early diagnosis and prevention are important to avoid a transition from preclinical HF stage to clinically overt HFpEF. Echocardiography with LA strain analysis and exercise stress echocardiography have the potential to identify patients with undiagnosed HFpEF, thus facilitating several preventive and therapeutic interventions. In this review, the development, measurement, and clinical application of LA strain are summarized and future perspectives in preventive medicine, accurate diagnosis, and therapeutic guidance for patients with HF are discussed.

Indexed as

Atrial Function, LeftEchocardiographyHeart AtriaHeart FailureAtrial FibrillationEchocardiography, StressHumansStroke VolumeExercise stress echocardiographyHeart failure with preserved ejection fractionLeft atrial functionLeft atrial strainLeft ventricular diastolic functionLeft ventricular filling pressure

Identifiers

PMID40608278
PMCPMC12378494

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.