Evidence map›Paper›PMID 40608241›Full record

ArticleAnnals of biomedical engineering2025

Progressive Collapsing Foot Deformity: Multi-bone Modeling and Joint Level Measurements.

Kassidy Knutson, Andrew C Peterson, Rich J Lisonbee, Takuma Miyamoto, Nicola Krähenbühl, Amy L Lenz

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Article in Annals of biomedical engineering, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Kassidy KnutsonDepartment of Orthopaedics, University of Utah, 590 Wakara Way, Salt Lake City, UT, 84108, USA.
Andrew C PetersonDepartment of Orthopaedics, University of Utah, 590 Wakara Way, Salt Lake City, UT, 84108, USA.
Rich J LisonbeeDepartment of Orthopaedics, University of Utah, 590 Wakara Way, Salt Lake City, UT, 84108, USA.
Takuma MiyamotoDepartment of Orthopaedics, University of Utah, 590 Wakara Way, Salt Lake City, UT, 84108, USA.
Nicola KrähenbühlDepartment of Orthopaedics, University Hospital Basel, Spitalstrasse 21, 4031, Basel, Switzerland. nicola.kraehenbuehl@usb.ch.
Amy L LenzDepartment of Orthopaedics, University of Utah, 590 Wakara Way, Salt Lake City, UT, 84108, USA. amy.lenz@utah.edu.ORCID http://orcid.org/0000-0003-2998-0906

Funding

ShapeWorks in the CloudR01AR076120 · NIAMS · UNIVERSITY OF UTAH · PI ELHABIAN, SHIREEN YOUSSEF · 2019 to 2024
$2.7M
Classification of Ankle Osteoarthritis Severity from Weightbearing Computed Tomography Using Statistical Shape Modeling and Machine LearningK01AR080221 · NIAMS · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Amy L. Lenz · 2022 to 2026
$707k
NIAMS NIH HHS K01 AR080221NIAMS NIH HHS K01AR080221NIAMS NIH HHS R01AR076120NIBIB NIH HHS U224EB029011
6 · The paper itself

Abstract

purposeThe objective of this study was to characterize joint level morphology and alignment differences across stages of progressive collapsing foot deformity (PCFD) within the talocrural, subtalar, talonavicular, and calcaneocuboid joints using multi-bone statistical shape modeling (SSM) and joint distance measurements from weightbearing computed tomography (WBCT) scans. This was achieved by employing multi-bone SSM in conjunction with precise joint measurement analysis, utilizing WBCT scans to investigate the intricate changes within the talocrural, subtalar, talonavicular, and calcaneocuboid joints.

methodsA retrospective analysis was conducted on patients with PCFD who failed conservative treatment. Two groups of 20 feet each were formed for flexible PCFD and rigid PCFD, with 27 additional feet identified as asymptomatic controls. All 67 participants underwent a WBCT scan, and 3D models were created as inputs for multi-bone SSM and joint distance measures.

resultsThe first principal component analysis mode contained 45.8% of the variation in the population while the second mode contained 13.3% of the variation and the third mode contained 6.4% of variation accounting for 65.6% of the overall variation in the multi-bone model. Joint space distance measurement differences were observed between all three groups for all articulations. The primary difference between flexible PCFD and rigid PCFD multi-bone SSM was a statistically significant medial shift of alignment of the talar neck, resulting in worsened peritalar subluxation.

conclusionPCFD is quantifiably variable across a clinical population when evaluating joint level measurements as well as morphologic and alignment variations. Talonavicular joint malalignment severity may be a clinical key in distinguishing between stages of PCFD.

Indexed as

Foot DeformitiesModels, BiologicalAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesTomography, X-Ray ComputedJoint Space DistancePrincipal Component AnalysisProgressive Collapsing Foot DeformityStatistical Shape ModelingWeightbearing Computed Tomography

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.