Evidence map›Paper›PMID 40608236›Full record

ArticleQuality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation2025

Psychometric testing of two respiratory bolt-on items to EQ-5D-5L in patients with obstructive airway diseases.

Ai-Ping Chua, Mathieu F Janssen, Ling-Jie Cheng, Jan V Busschbach, Nan Luo

Abstract read
PubMed Publisher
In one paragraph

Article in Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ai-Ping ChuaDivision of Respiratory Medicine, Department of Medicine, JurongHealth Campus, National University Health System, Singapore, Singapore. ai_ping_chua@nuhs.edu.sg.ORCID http://orcid.org/0000-0003-1773-5049
Mathieu F JanssenSection Medical Psychology and Psychotherapy, Department of Psychiatry, Erasmus Medical Centre, Rotterdam, Netherlands.
Ling-Jie ChengSaw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.
Jan V BusschbachSection Medical Psychology and Psychotherapy, Department of Psychiatry, Erasmus Medical Centre, Rotterdam, Netherlands.
Nan LuoSaw Swee Hock School of Public Health, National University of Singapore, Singapore, Singapore.

Funding

EuroQol Research Foundation #274-RA
6 · The paper itself

Abstract

objectivesTwo recently developed respiratory bolt-ons were shown to improve the construct validity of EQ-5D-5L among community-treated patients with obstructive airway disease (OAD). We evaluated their psychometric properties, including responsiveness and reliability in a specialist-managed OAD cohort.

methodsWe performed in-depth interviews with ten OAD patients and ten clinicians to assess their content validity. We administered the Saint George's Respiratory Questionnaire (SGRQ), EQ-5D-5L and two respiratory bolt-on items, (physical impediment, R1 & symptoms, R2) in adult OAD patients at baseline and follow-up visits. We used the baseline data to compare among four EQ-5D versions, EQ-5D-5L, + R1, + R2 & + R1R2: (1) ceiling using individual item responses; and (2) Spearman's rho correlations (R

resultsPsychometric properties of the respiratory bolt-ons proved to be acceptable. We included 184 patients with a mean age of 54 (standard deviation, 18) years at baseline, and 120 at follow-up at 2.8 (standard deviation, 1.7) months. The ceilings were nullified in + R1, + R2 and + R1R2. Construct validity and responsiveness were consistently higher in + R2 and + R1R2 compared to EQ-5D-5L, while reliability remained comparable among the four versions.

conclusionsRespiratory bolt-ons demonstrated good content validity and enhanced the psychometric properties of EQ-5D-5L in OAD.

Indexed as

PsychometricsPulmonary Disease, Chronic ObstructiveQuality of LifeAdultAgedFemaleHumansInterviews as TopicMaleMiddle AgedReproducibility of ResultsSurveys and QuestionnairesHealth statusMixed methodPatient-reported outcomePulmonaryQuality of lifeUtility

Identifiers

PMID40608236

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.