ReviewStem cell reviews and reports2025
Adipose-Derived Stem Cells at the Crossroads of Obesity and Cancer.
Review in Stem cell reviews and reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Adipocytes in cancer a metabolic paradox and the dawn of novel therapeutics.Discover oncology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
Abstract
Obesity is a major concern for public health and is associated with a higher risk of various types of cancer. Understanding the fundamental mechanisms of this relationship is essential for effective cancer prevention and treatment. Adipose-derived stem cells (ADSCs) are a specialized subtype of mesenchymal stem cells (MSCs) extracted from adipose tissue. These cells have the ability to undergo lineage-specific differentiation into adipocytes, osteoblasts, and chondrocytes. Although ADSCs have significant therapeutic potential, existing studies have indicated that they may facilitate cancer initiation, progression, and recurrence through multiple pathways, including their capacity to facilitate tumor cell proliferation, epithelial-to-mesenchymal transition (EMT), angiogenesis, formation of cancer stem cells (CSCs), immune evasion, and resistance to therapy. Obese individuals have a higher amount of adipose tissue containing an abundance of ADSCs compared to normal individuals, highlighting the possible role of ADSCs in the link between obesity and cancer. In this review, we have explored the effects of ADSCs on cancer initiation, promotion, and progression and put forward a hypothetical model to explain the elevated risk of cancer among obese patients.
Indexed as
Identifiers
40608181What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.