Evidence map›Paper›PMID 40608100›Full record

ReviewAdvances and technical standards in neurosurgery2025

Surgical Treatment of Cushing's Disease: The Lessons Learned.

L de Nijs, E Fomekong, D Maiter, C Raftopoulos

Abstract readReview
PubMed Publisher
In one paragraph

Review in Advances and technical standards in neurosurgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

L de NijsCliniques Universitaires St-Luc, Université Catholique de Louvain, Brussels, Belgium.
E FomekongCliniques Universitaires St-Luc, Université Catholique de Louvain, Brussels, Belgium.
D MaiterCliniques Universitaires St-Luc, Université Catholique de Louvain, Brussels, Belgium.
C RaftopoulosCentre Hospitalier Interrégional Edith Cavell (CHIREC), Brussels, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This chapter aims to provide insightful guidance drawn from an updated litera ture search and the long experience of our multidisciplinary team in the surgical management of Cushing's disease. We will first compare the two primary TSS tech niques-microscopic and endoscopic-emphasizing the importance of surgical expertise. We will also discuss new imaging modalities, which may improve the preoperative localization of corticotroph microadenomas. Addressing scenarios where extensive imaging fails to detect pituitary tumors, the chapter analyzes diag nostic challenges, offering guidance on improving localization and effective surgi cal strategies, including the contribution of neuronavigation systems and intraoperative MRI (iMRI). This comprehensive exploration aims to empower clini cians in managing the complexities of Cushing's disease, from accurate localization to advanced surgical techniques and beyond.

Indexed as

AdenomaNeurosurgical ProceduresPituitary ACTH HypersecretionHumansMagnetic Resonance ImagingNeuronavigationPituitary Neoplasms11C-methionine positron emission tomographyCushing’s diseaseEndoscopic transsphenoidal surgeryMicroscopic transsphenoidal surgeryMRI-negative Cushing’s disease

Identifiers

PMID40608100

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.