Evidence map›Paper›PMID 40608052›Full record

ArticleeLife2025

Responses to membrane potential-modulating ionic solutions measured by magnetic resonance imaging of cultured cells and in vivo rat cortex.

Kyeongseon Min, Sungkwon Chung, Seung-Kyun Lee, Jongho Lee, Phan Tan Toi, Daehong Kim, Jung Seung Lee, Jang-Yeon Park

Abstract read
In one paragraph

Article in eLife, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kyeongseon MinDepartment of Electrical and Computer Engineering, Seoul National University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0001-7614-2089
Sungkwon ChungDepartment of Physiology, Sungkyunkwan University School of Medicine, Suwon, Republic of Korea.ORCID https://orcid.org/0000-0003-0505-8773
Seung-Kyun LeeDepartment of Biomedical Engineering, Sungkyunkwan University, Seoul, Republic of Korea.
Jongho LeeDepartment of Electrical and Computer Engineering, Seoul National University, Seoul, Republic of Korea.
Phan Tan ToiDepartment of Biomedical Engineering, Sungkyunkwan University, Seoul, Republic of Korea.
Daehong KimNational Cancer Center, Goyang-si, Republic of Korea.
Jung Seung LeeDepartment of Biomedical Engineering, Sungkyunkwan University, Seoul, Republic of Korea.
Jang-Yeon ParkDepartment of Biomedical Engineering, Sungkyunkwan University, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-0586-1606

Funding

Commercializations Promotion Agency for R and D Outcomes NTIS1711198890National Research Foundation of Korea 2019M3C7A1031993National Research Foundation of Korea 2019M3C7A1031994National Research Foundation of Korea 2023R1A2C3007075
6 · The paper itself

Abstract

Membrane potential plays a crucial role in various cellular functions. However, existing techniques for measuring membrane potential are often invasive or have limited recording depth. In contrast, MRI offers noninvasive imaging with desirable spatial resolution over large areas. This study investigates the feasibility of utilizing MRI to detect responses of cultured cells and in vivo rat cortex to membrane potential-modulating ionic solutions by measuring magnetic resonance parameters. Our findings reveal that depolarizing (or hyperpolarizing) ionic solutions increase (or decrease) the

Indexed as

Cerebral CortexIonsMagnetic Resonance ImagingMembrane PotentialsAnimalsCells, CulturedRatsSolutionsIonsSolutionsjurkatmagnetic resonance imagingmagnetization transfermembrane potentialneurosciencephysics of living systemsratSH-SY5YT2 relaxation time

Identifiers

PMID40608052
PMCPMC12226016

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.