Evidence map›Paper›PMID 40607763›Full record

ArticleJournal of clinical laboratory analysis2025

Drug Resistance and Epidemiological Analysis of Carbapenem-Resistant Enterobacteriaceae in a Brain and Psychiatric Hospital of South China.

Lei Yue, Xiumei Zhu, Yuyan Kuang, Yulong Lin, Haiying Liu

Abstract read
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In one paragraph

Article in Journal of clinical laboratory analysis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Lei YueClinical Laboratory, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.ORCID https://orcid.org/0000-0001-8738-0111
Xiumei ZhuClinical Laboratory, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Yuyan KuangClinical Laboratory, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Yulong LinClinical Laboratory, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.
Haiying LiuClinical Laboratory, The Affiliated Brain Hospital, Guangzhou Medical University, Guangzhou, Guangdong, People's Republic of China.

Funding

Guangzhou Health Science and Technology General Guidance Project 20231A010039Guangzhou Municipal Key Discipline in Medicine (2025-2027)Guangzhou Municipal Science and Technology Project 2023A03J0851
6 · The paper itself

Abstract

backgroundCarbapenem-resistant Enterobacteriaceae (CRE) has increasingly become a global health problem, and the drug resistance and epidemiology of its infection are important for disease prevention and control.

methodsThe CRE isolates detected in the hospital from July 2021 to April 2023 were collected, then the antibiotic sensitivity was detected by an automatic microbial analyzer. Polymerase chain reaction (PCR) was performed to detect carbapenem-resistance genes. The homology and epidemiological characteristics of the strains of Enterobacteriaceae were analyzed by repeated common sequence PCR(ERIC-PCR).

resultsA total of 94 non-repeating CRE isolates were collected mainly from the respiratory tract (67.02%) and urinary tract (22.34%). Among these, 73 strains (77.66%) were carbapenem-resistant Klebsiella pneumoniae (CRKP), while 21 strains (22.34%) were carbapenem-resistant Escherichia coli (CREC). Antibiotic susceptibility testing revealed a low resistance rate to tigecycline (2.13%). Analysis of CRE resistance genes demonstrated that blaKPC accounted for 93.15% of CRKP isolates (68/73), while blaNDM was present in 90.48% of CREC isolates (19/21). In the homology analysis, CRKP isolates were divided into five clusters with C

conclusionsCRE infection in this hospital has high homology and wide distribution; it is necessary to strengthen prevention and control measures to control CRE nosocomial infection spread.

Indexed as

Anti-Bacterial AgentsCarbapenem-Resistant EnterobacteriaceaeEnterobacteriaceae InfectionsAdultCarbapenemsChinaFemaleHospitals, PsychiatricHumansKlebsiella pneumoniaeMaleMicrobial Sensitivity TestsMiddle AgedAnti-Bacterial AgentsCarbapenemsCarbapenemasedrug resistance geneEnterobacteralesepidemiology

Identifiers

PMID40607763
PMCPMC12329348

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