Evidence map›Paper›PMID 40607745›Full record

ArticleThe Journal of organic chemistry2025

Influence of Halogen Atoms and the Reactivity of Nucleophiles on Reactions of Tetrahydropyran and Tetrahydrofuran Acetals with

Krystyna M Demkiw, Wouter A Remmerswaal, Asma Sheikh, Ibrahim N Sheikh, Collin H Witt, Jeroen D C Codée, K A Woerpel

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of organic chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Krystyna M DemkiwDepartment of Chemistry, New York University, 100 Washington Square East, New York, New York 10003, United States.ORCID 0000-0001-5457-3291
Wouter A RemmerswaalLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, Leiden 2300 RA, The Netherlands.ORCID 0000-0002-1040-4311
Asma SheikhDepartment of Chemistry, New York University, 100 Washington Square East, New York, New York 10003, United States.
Ibrahim N SheikhDepartment of Chemistry, New York University, 100 Washington Square East, New York, New York 10003, United States.
Collin H WittDepartment of Chemistry, New York University, 100 Washington Square East, New York, New York 10003, United States.ORCID 0000-0002-1797-2469
Jeroen D C CodéeLeiden Institute of Chemistry, Leiden University, Einsteinweg 55, Leiden 2300 RA, The Netherlands.ORCID 0000-0003-3531-2138
K A WoerpelDepartment of Chemistry, New York University, 100 Washington Square East, New York, New York 10003, United States.ORCID 0000-0002-8515-0301

Funding

Stereoselective Reactions of Oxocarbenium Ions and Related IntermediatesR35GM148203 · NIGMS · NEW YORK UNIVERSITY · PI KEITH ALLEN WOERPEL · 2023 to 2026
$1.9M
Acquisition of a Cryoprobe for a 600 MHz NMR SpectrometerS10OD016343 · OD · NEW YORK UNIVERSITY · PI KROGSGAARD, MICHELLE, TRAASETH, NATHANIEL J. · 2014 to 2014
$360k
NIGMS NIH HHS R35 GM148203NIH HHS S10 OD016343
6 · The paper itself

Abstract

Tetrahydropyran acetals bearing a fluorine atom adjacent to the acetal carbon atom can undergo highly stereoselective substitution reactions with nucleophilic alkenes to give the 1,2-

Identifiers

PMID40607745
PMCPMC12281571

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.