Evidence map›Paper›PMID 40607494›Full record

ArticleRespirology case reports2025

Allergic Bronchopulmonary Aspergillosis With Elevated Serum Tumour Marker Levels.

Hiroaki Ishikawa, Mari Anzai, Ayaka Kishimoto, Tomohiro Namiki, Ryusei Nakagawa, Hiroya Sunabe, Toshihide Inui, Hiroko Watanabe, Yuichi Dai, Tohru Sakamoto

Abstract read
In one paragraph

Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hiroaki IshikawaDepartment of Respiratory Medicine Tsukuba Memorial Hospital Tsukuba Japan.
Mari AnzaiDepartment of Respiratory Medicine Tsukuba Memorial Hospital Tsukuba Japan.
Ayaka KishimotoDepartment of Respiratory Medicine Tsukuba Memorial Hospital Tsukuba Japan.
Tomohiro NamikiDepartment of Respiratory Medicine Tsukuba Memorial Hospital Tsukuba Japan.
Ryusei NakagawaDepartment of Respiratory Medicine Tsukuba Memorial Hospital Tsukuba Japan.
Hiroya SunabeDepartment of Respiratory Medicine Tsukuba Memorial Hospital Tsukuba Japan.
Toshihide InuiDepartment of Respiratory Medicine Tsukuba Memorial Hospital Tsukuba Japan.
Hiroko WatanabeDepartment of Respiratory Medicine Tsukuba Memorial Hospital Tsukuba Japan.
Yuichi DaiDepartment of Diagnostic Pathology Tsukuba Memorial Hospital Tsukuba Japan.
Tohru SakamotoDepartment of Respiratory Medicine Tsukuba Memorial Hospital Tsukuba Japan.ORCID https://orcid.org/0000-0002-8876-1466

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the case of a 56-year-old woman diagnosed with allergic bronchopulmonary aspergillosis (ABPA) who showed multiple nodular shadows on a chest x-ray. The patient displayed increased blood eosinophil counts and elevated serum levels of tumour markers including carcinoembryonic antigen (CEA), squamous cell carcinoma (SCC) antigen, and sialyl Lewis X (SLX). Computed tomography revealed that these abnormal shadows reflected central bronchiectasis with mucus plugs. The patient was started on prednisolone, which immediately normalised peripheral blood eosinophils. In contrast, serum CEA, SCC antigen, and SLX levels decreased slowly along with the gradual disappearance of the mucus plugs. ABPA with mucus plugs in the bronchi may present with elevated levels of serum tumour markers as well as nodular shadows on chest x-rays, requiring differentiation from malignancy.

Indexed as

allergic bronchopulmonary aspergillosiscarcinoembryonic antigenhigh‐attenuation mucussialyl Lewis Xsquamous cell carcinoma antigen

Identifiers

PMID40607494
PMCPMC12213056

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.