Evidence map›Paper›PMID 40607493›Full record

ReviewNpj biological timing and sleep2025

The cyanobacterial circadian clock.

Yong-Gang Chang, Andy LiWang

Abstract readReview
In one paragraph

Review in Npj biological timing and sleep, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Genotype-phenotype modeling of light ecotypes inbioRxiv : the preprint server for biology · 2026
    Article
  3. Frontiers in microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Yong-Gang ChangDepartment of Medicine, Monash University, Melbourne, VIC Australia.
Andy LiWangDepartment of Chemistry & Biochemistry, University of California, Merced, CA USA.

Funding

Temperature and metabolic compensation mechanisms in a circadian clock systemR35GM144110 · NIGMS · UNIVERSITY OF CALIFORNIA, MERCED · PI Andy LiWang · 2022 to 2026
$2.2M
NIGMS NIH HHS R35 GM144110
6 · The paper itself

Abstract

This review summarizes recent advances in understanding the cyanobacterial circadian clock, emphasizing how the KaiA, KaiB, and KaiC proteins generate robust, temperature-compensated rhythms through ordered phosphorylation, conformational switching, and dynamic protein interactions. A comparative analysis of 30 KaiC structures under different states of phosphorylation and nucleotide binding is also presented. Together, these structural and mechanistic insights illuminate fundamental principles of biological timekeeping and evolutionary adaptations in these photosynthetic prokaryotes.

Indexed as

BiochemistryCircadian rhythm signalling peptides and proteins

Identifiers

PMID40607493
PMCPMC12208873

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.