Evidence map›Paper›PMID 40607440›Full record

ArticleFrontiers in immunology2025

Immunoglobulin Y antibodies against colonization-related genes block the growth and infection of

Shiyuan Deng, Xiaoling Luo, Yunxiao Du, Rania G Elbaiomy, Weihan He, Rong Guo, Ahmed H El-Sappah, Xiaohong Jian, Yongmei Xie, Mohammed Bakeer and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Shiyuan DengDepartment of Biological Engineering, Sichuan University of Science & Engineering, Zigong, China.
Xiaoling LuoDepartment of Gastroenterology, Fushun People's Hospital, Zigong, China.
Yunxiao DuDepartment of Biological Engineering, Sichuan University of Science & Engineering, Zigong, China.
Rania G ElbaiomyDepartment of Biological Engineering, Sichuan University of Science & Engineering, Zigong, China.
Weihan HeDepartment of Biological Engineering, Sichuan University of Science & Engineering, Zigong, China.
Rong GuoDepartment of Gastroenterology, Fushun People's Hospital, Zigong, China.
Ahmed H El-SappahDepartment of Genetics, Faculty of Agriculture, Zagazig University, Zagazig, Egypt.
Xiaohong JianDepartment of Biological Engineering, Sichuan University of Science & Engineering, Zigong, China.
Yongmei XieState Key Laboratory of Biotherapy and Cancer Center, West China Hospital, Sichuan University, Chengdu, China.
Mohammed BakeerDivision of Hematology and Medical Oncology, Mayo Clinic, Jacksonville, FL, United States.
Zaixin LiDepartment of Biological Engineering, Sichuan University of Science & Engineering, Zigong, China.
Zhi ZhangDepartment of Biological Engineering, Sichuan University of Science & Engineering, Zigong, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Immunoglobulin Y (IgY) has emerged as a promising antibody therapy for the eradication of Methods: The recombinant antigens of five colonization-related genes - Results: These IgY antibodies can recognize the full-length antigens of Conclusion: Our results indicate that IgY antibodies against colonization-related genes can directly block the growth and infection of

Indexed as

Antibodies, BacterialHelicobacter InfectionsHelicobacter pyloriImmunoglobulinsAnimalsAntigens, BacterialCell LineChickensDisease Models, AnimalFemaleGastritisHumansMiceMice, Inbred BALB CAntibodies, BacterialAntigens, BacterialIgYImmunoglobulinseradication rategrowthHelicobacter pyloriimmunoglobulin Yinfection

Identifiers

PMID40607440
PMCPMC12213714

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.