Evidence map›Paper›PMID 40607352›Full record

ArticleFrontiers in veterinary science2025

Plasma procalcitonin and C-reactive protein concentrations in dogs with bacterial sepsis and non-infectious systemic inflammatory response syndrome.

Johanna Rompf, Bérénice Lutz, Katja-Nicole Adamik, Eliane Marti, Jelena Mirkovitch, Laureen Michèle Peters, Jennifer Eiermann, Gertraud Schüpbach-Regula, Bianca Hettlich, Barbara Willi and 1 more

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Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Johanna RompfDivision of Small Animal Internal Medicine, Department of Clinical Veterinary Science, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Bérénice LutzDivision of Small Animal Internal Medicine, Department of Clinical Veterinary Science, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Katja-Nicole AdamikSmall Animal Emergency and Critical Care Group, Department of Clinical Veterinary Science, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Eliane MartiDivision of Neurological Sciences, Department of Clinical Research and Veterinary Public Health, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Jelena MirkovitchDivision of Neurological Sciences, Department of Clinical Research and Veterinary Public Health, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Laureen Michèle PetersClinical Diagnostic Laboratory, Department of Clinical Veterinary Science, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Jennifer EiermannDivision of Small Animal Internal Medicine, Department of Clinical Veterinary Science, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Gertraud Schüpbach-RegulaVeterinary Public Health Institute, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Bianca HettlichSmall Animal Surgery Division, Department of Clinical Veterinary Science, Vetsuisse Faculty, University of Bern, Bern, Switzerland.
Barbara WilliClinic for Small Animal Internal Medicine, Vetsuisse Faculty, University of Zurich, Zürich, Switzerland.
Simone SchullerDivision of Small Animal Internal Medicine, Department of Clinical Veterinary Science, Vetsuisse Faculty, University of Bern, Bern, Switzerland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Procalcitonin is a well-established biomarker of bacterial infections in human medicine, used to guide initiation and duration of antimicrobial treatment. C-reactive protein (CRP) is a frequently used marker of inflammation in dogs, but is not specific for bacterial infection. The main objective of this study was to determine kinetics of plasma PCT (pPCT) and CRP in dogs with sepsis, non-infectious systemic inflammatory response syndrome (nSIRS) and healthy dogs. This prospective, observational study included 17 dogs with sepsis, 16 with nSIRS and 15 healthy dogs. Hematologic parameters, pPCT and CRP were assessed on days 1, 2 and 3 in healthy dogs and on days 1, 2, 3 and 4 in dogs with nSIRS or sepsis. The shortened Acute Patient Physiologic and Laboratory Evaluation (APPLE

Indexed as

antimicrobial stewardshipbiomarkercaninesepsisSIRS

Identifiers

PMID40607352
PMCPMC12213344

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.