Evidence map›Paper›PMID 40607315›Full record

ReviewClinical parkinsonism & related disorders2025

Time to add two new disorders to neuropsychiatric aspects of Parkinson's disease.

Stefano Luca Sensi, Matteo Alessandro De Rosa, Mirella Russo, Astrid Thomas, Marco Onofrj

Abstract readReview
In one paragraph

Review in Clinical parkinsonism & related disorders, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Stefano Luca SensiDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Matteo Alessandro De RosaDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Mirella RussoDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Astrid ThomasDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.
Marco OnofrjDepartment of Neuroscience, Imaging and Clinical Sciences, "G. d'Annunzio" University of Chieti-Pescara, 66100 Chieti, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Recent reviews have explored Parkinson's Disease (PD) through psychiatric lenses. However, emerging literature allows to go beyond psychosis, depression, and impulse control disorders. Two key emerging themes are prominent: firstly, studies accrued in the past 13 years challenge prevailing views by demonstrating Somatic Symptom Disorders/Somatoform Disorders (SSD-SD) significantly participate in the PD phenotype, with relevant treatment implications. Secondly, epidemiological data reveal a link between Bipolar Spectrum Disorders (BSD) and PD, prompting a reconsideration of Impulse Control Disorder/Hedonistic Homeostatic Dysregulation (ICD/HHD) in PD. Furthermore, behaviors akin to BSD symptoms during manic states are observed in PD, suggesting shared neurobiological underpinnings. Our proposed review tackles these themes, dissecting the impact of SSD-SD on PD and highlighting the BSD-PD convergence. This approach has implications for tailored psychotherapeutic techniques targeting psychosomatic and functional neurologic disorders within the context of PD care. Moreover, recognizing the blurred lines between neurology and psychiatry in PD underscores the importance of a holistic, interdisciplinary approach. As these findings challenge established assumptions and offer new avenues for patient care, we must promote our understanding of PD's intricate neuropsychiatric dimensions.

Indexed as

Bipolar Spectrum DisordersNeuropsychiatric DisordersParkinson’s DiseaseSomatic Symptom Disorders

Identifiers

PMID40607315
PMCPMC12221469

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.