Evidence map›Paper›PMID 40607305›Full record

ArticleAnnals of gastroenterological surgery2025

Short-term outcomes of intracorporeal anastomosis in laparoscopic colectomy for colon cancer: A nationwide, multi-institutional cohort study in Japan (ICAN study).

Tomohiro Yamaguchi, Keitaro Tanaka, Jun Watanabe, Hiroki Hamamoto, Atsushi Nishimura, Fumihiko Fujita, Hirokazu Suwa, Masaaki Ito, Kazushige Kawai, Junichiro Hiro and 9 more

Abstract read
In one paragraph

Article in Annals of gastroenterological surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Article
  3. Essential Updates 2024-2026: Advances in Colorectal Cancer Surgery.Annals of gastroenterological surgery · 2026
    Review
  4. Article
  5. Article
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Tomohiro YamaguchiDepartment of Gastroenterological Surgery Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.ORCID https://orcid.org/0000-0002-5023-0985
Keitaro TanakaDepartment of General and Gastroenterological Surgery Osaka Medical and Pharmaceutical University Takatsuki Japan.
Jun WatanabeDepartment of Surgery, Gastroenterological Center Yokohama City University Medical Center Yokohama Kanagawa Japan.ORCID https://orcid.org/0000-0002-7187-3664
Hiroki HamamotoDepartment of General and Gastroenterological Surgery Osaka Medical and Pharmaceutical University Takatsuki Japan.ORCID https://orcid.org/0000-0002-2294-4673
Atsushi NishimuraDepartment of Surgery, Institute of Gastroenterology Nagaoka Chuo General Hospital Niigata Japan.
Fumihiko FujitaDepartment of Surgery Kurume University School of Medicine Fukuoka Japan.
Hirokazu SuwaDepartment of Surgery Yokosuka Kyosai Hospital Yokosuka Japan.
Masaaki ItoDepartment of Colorectal Surgery National Cancer Center Hospital East Chiba Japan.ORCID https://orcid.org/0000-0002-1101-2707
Kazushige KawaiDepartment of Colorectal Surgery Tokyo Metropolitan Cancer and Infectious Diseases Center Komagome Hospital Tokyo Japan.ORCID https://orcid.org/0000-0002-5881-0036
Junichiro HiroDepartment of Surgery Fujita Health University Toyoake Aichi Japan.
Seiichiro YamamotoDepartment of Gastroenterological Surgery Tokai University School of Medicine Isehara Kanagawa Japan.
Sho NambaraDepartment of Gastroenterological Surgery Cancer Institute Hospital of Japanese Foundation for Cancer Research Tokyo Japan.
Masato OtaDepartment of General and Gastroenterological Surgery Osaka Medical and Pharmaceutical University Takatsuki Japan.
Yuri ItoDepartment of Medical Statistics, Research & Development Center Osaka Medical and Pharmaceutical University Takatsuki Japan.
Junji OkudaDepartment of General and Gastroenterological Surgery Osaka Medical and Pharmaceutical University Takatsuki Japan.
Masafumi InomataDepartment of Gastroenterological and Pediatric Surgery Oita University Faculty of Medicine Yufu Japan.
Masahiko WatanabeDepartment of Surgery Kitasato University Kitasato Institute Hospital Tokyo Japan.
Takeshi NaitohDepartment of Lower Gastrointestinal Surgery Kitasato University School of Medicine Sagamihara Japan.ORCID https://orcid.org/0000-0003-4169-6334
ICAN Collaborative Study Group of the Japan Society of Laparoscopic Colorectal Surgery

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Several randomized controlled trials and meta-analyses have demonstrated the potential advantages of intracorporeal over extracorporeal anastomosis. However, the heterogeneity and small samples of these studies complicate drawing clear conclusions regarding such advantages. In this nationwide, multicenter, retrospective cohort study, we aimed to clarify the benefits of intracorporeal over extracorporeal anastomosis in patients undergoing laparoscopic colectomy for colon cancer. Methods: This study included 46 institutions. Patients with clinical stage 0-III colon adenocarcinoma who underwent laparoscopic colectomy between January 2020 and December 2021 were evaluated. The effect of intracorporeal anastomosis on short-term outcomes compared to extracorporeal anastomosis was assessed using propensity score matching. Results: A total of 1245 patients (intracorporeal, Conclusions: Intracorporeal anastomosis showed advantages over extracorporeal anastomosis in terms of blood loss, intraoperative vascular injury (potentially), bowel recovery, and length of hospital stay, despite the longer operative time.

Indexed as

colectomycolonic neoplasmslaparoscopysurgical anastomosistreatment outcomes

Identifiers

PMID40607305
PMCPMC12211091

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.