ArticleAnnals of gastroenterological surgery2025
Impact of primary tumor clinicopathological factors on prognosis after hepatic resection for rectal liver metastases.
Article in Annals of gastroenterological surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed.
- Article
- Management Strategies for Disappearing Colorectal Liver Metastases After Systemic Chemotherapy: Long-Term Outcomes and Preoperative Prediction of 'True Complete Response'.Annals of gastroenterological surgery · 2026Article
- Impact of primary tumor clinicopathological factors on prognosis after hepatic resection for rectal liver metastases.Annals of gastroenterological surgery · 2025Article
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10 authors.
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Abstract
Background: Treatment of liver metastases from rectal cancer has been considered based on research data on liver metastases from colorectal cancer. This study aimed to clarify the impact of clinicopathological factors of the primary lesion, including rectal cancer-specific factors such as lateral lymph node metastasis, on the prognosis after liver resection. Methods: This was a single-center retrospective study of patients undergoing curative surgical treatment for resectable liver metastases from rectal cancer from January 2010 to June 2023. Prognostic factors were investigated using univariable and multivariable analyses. Results: The cohort consisted of 113 males and 44 females, with a median age of 60 years. Lateral lymph node dissection was performed in 48 patients, of which 11 had positive nodes. Multivariable analysis revealed lateral lymph node metastasis (HR 5.86; 95% CI 2.40-14.2; Conclusions: Lateral lymph node metastasis and perineural invasion of the primary tumor were prognostic factors after resection of rectal liver metastases. Patients with these factors required nonsurgical treatment in the early postoperative period.
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