Evidence map›Paper›PMID 40607210›Full record

ReviewInterventional cardiology (London, England)2025

Management of Coronary Artery Disease in the Context of Transcatheter Aortic Valve Implantation: A Systematic Review and Meta-analysis of Percutaneous Coronary Intervention Timing and an Algorithmic Approach to Management.

Cian Murray, Caoimhe Ryan, Michael Cronin, Hugo Temperley, Niall O'Sullivan, Stephen O'Connor, Andrew Maree, Mark Hensey

Abstract readReview
In one paragraph

Review in Interventional cardiology (London, England), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Cian MurrayCardiology Department, St James's Hospital Dublin, Ireland.ORCID https://orcid.org/0000-0002-4838-4379
Caoimhe RyanCardiology Department, Mater Misericordiae University Hospital Dublin, Ireland.ORCID https://orcid.org/0009-0005-9458-1305
Michael CroninCardiology Department, St James's Hospital Dublin, Ireland.ORCID https://orcid.org/0000-0003-1088-1668
Hugo TemperleyRadiology Department, St James's Hospital Dublin, Ireland.ORCID https://orcid.org/0000-0001-9151-3431
Niall O'SullivanRadiology Department, St James's Hospital Dublin, Ireland.ORCID https://orcid.org/0000-0002-6241-7819
Stephen O'ConnorCardiology Department, St James's Hospital Dublin, Ireland.ORCID https://orcid.org/0000-0002-6539-0375
Andrew MareeCardiology Department, St James's Hospital Dublin, Ireland.ORCID https://orcid.org/0000-0002-0002-5828
Mark HenseyCardiology Department, St James's Hospital Dublin, Ireland.ORCID https://orcid.org/0000-0001-9270-6446

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Transcatheter aortic valve implantation (TAVI) is widely performed for severe aortic stenosis (AS), often accompanied by coronary artery disease (CAD). The optimal management of CAD in TAVI patients remains uncertain. This study reviews the evidence on percutaneous coronary intervention (PCI) timing in TAVI, and proposes an algorithmic approach for CAD management. Methods: A comprehensive search of PubMed, EMBASE and Cochrane identified studies comparing PCI timing strategies in TAVI patients. Results: Thirteen studies with 15,412 participants were included. Mortality at 30 days (OR 5.70; 95% CI [1.34-24.36]) and 2 years (OR 4.40; 95% CI [2.60-7.44]) were significantly higher in the combined pre-TAVI and concomitant PCI group than in the post-TAVI cohort. Rates of other periprocedural complications, such as stroke and bleeding, varied across studies. Conclusion: There is no clear consensus on PCI timing in TAVI due to a lack of high-quality randomised data. An individualised, algorithmic approach is proposed for managing CAD in patients undergoing TAVI.

Indexed as

coronary artery diseasepercutaneous coronary interventiontimingTranscatheter aortic valve implantation

Identifiers

PMID40607210
PMCPMC12215414

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.