Evidence map›Paper›PMID 40607161›Full record

ArticleNeuropsychiatric disease and treatment2025

Blood Uric Acid in Mild Cognitive Impairment: A Cross-Sectional Study of Older Chinese Adults.

Lingling Xue, Xifeng Xiao, Xin'e Mao, Xiaoli Zhang, Yongbing Liu, Beibei Wu

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Article in Neuropsychiatric disease and treatment, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

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4 · The record

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5 · Who and what money

Authors and funding

6 authors.

Lingling XueDepartment of Nursing, Yangzhou Maternal and Child Health Care Hospital Affiliated to Yangzhou University, Yangzhou, People's Republic of China.
Xifeng XiaoDepartment of Nursing, Yangzhou Maternal and Child Health Care Hospital Affiliated to Yangzhou University, Yangzhou, People's Republic of China.
Xin'e MaoGeriatric Unit, Northern Jiangsu People's Hospital, Yangzhou, People's Republic of China.
Xiaoli ZhangDepartment of Nursing, Yangzhou Maternal and Child Health Care Hospital Affiliated to Yangzhou University, Yangzhou, People's Republic of China.
Yongbing LiuDepartment of Nursing, School of Nursing and public Health, Yangzhou University, Yangzhou, People's Republic of China.
Beibei WuDepartment of Nursing, Yangzhou Maternal and Child Health Care Hospital Affiliated to Yangzhou University, Yangzhou, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Previous studies focused on the association between uric acid (UA) as an antioxidant and cognitive impairment have been limited in scope and obtained contradictory results. Therefore, we investigated whether low blood UA levels were related to mild cognitive impairment (MCI) in a cross-sectional study. Methods: This study included 231 elderly Chinese adults 60 years and over. We used the MMSE and MoCA to evaluate cognitive function, and fasting venous blood to measure UA concentration. The relationship between blood UA and cognitive impairment was analyzed with multivariate analysis of variance, controlling for demographic information, physical exercise, lifestyle and laboratory results. Results: A total of 90 (38.96%) participants were healthy and 141 (61.04%) had MCI. Compared with the healthy group, MCI patients were more likely to have fewer years of education, inactivity and lower UA levels. UA levels were significantly lower in MCI patients than healthy individuals ( Conclusion: Lower UA levels were associated with worse cognitive function; therefore, controlling UA levels within a suitable range may slow the progression of cognitive disorders.

Indexed as

differences between groupsfactorsmild cognition impairmenturic acid

Identifiers

PMID40607161
PMCPMC12219187

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