Evidence map›Paper›PMID 40607139›Full record

ArticleTrends in analytical chemistry : TRAC2024

Nanoplasmonics biosensors: At the frontiers of biomedical diagnostics.

Aidan J Canning, Joy Q Li, Supriya Atta, Hsin-Neng Wang, Tuan Vo-Dinh

Abstract read
In one paragraph

Article in Trends in analytical chemistry : TRAC, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Aidan J CanningFitzpatrick Institute for Photonics, Duke University, Durham, NC, USA.
Joy Q LiFitzpatrick Institute for Photonics, Duke University, Durham, NC, USA.
Supriya AttaFitzpatrick Institute for Photonics, Duke University, Durham, NC, USA.
Hsin-Neng WangFitzpatrick Institute for Photonics, Duke University, Durham, NC, USA.
Tuan Vo-DinhFitzpatrick Institute for Photonics, Duke University, Durham, NC, USA.

Funding

RAPID System for Early Detection of Head and Neck Cancer in Low-Resource SettingsR01DE030455 · NIDCR · DUKE UNIVERSITY · PI WALTER Tsong LEE, Tuan Vo-Dinh · 2022 to 2026
$2.7M
Plasmonic nanoparticle-mediated immunotherapy to treat metastatic cancerR01EB028078 · NIBIB · DUKE UNIVERSITY · PI VO-DINH, TUAN · 2019 to 2022
$2.1M
Integrated Acoustofluidic Plasmonic Molecular Diagnostic System for Detecting MicroRNA BiomarkersR01GM135486 · NIGMS · DUKE UNIVERSITY · PI VO-DINH, TUAN · 2020 to 2023
$1.8M
Nanoplasmonics-based molecular analysis tool for molecular biomarkers of cancerR21CA196426 · NCI · DUKE UNIVERSITY · PI VO-DINH, TUAN · 2015 to 2017
$676k
Bloodborne tropical pathogen detection using multiple nanophotonic arraysR21AI120981 · NIAID · DUKE UNIVERSITY · PI TAYLOR, STEVE MYER, VO-DINH, TUAN · 2016 to 2017
$407k
Gates Foundation INV-040790NCI NIH HHS R21 CA196426NIAID NIH HHS R21 AI120981NIBIB NIH HHS R01 EB028078NIDCR NIH HHS R01 DE030455NIGMS NIH HHS R01 GM135486
6 · The paper itself

Abstract

This article presents an overview of various nanoplasmonics biosensors and their diverse applications, focusing on recent developments in our laboratory. We describe the versatility and effectiveness of different plasmonics-active platforms, ranging from solid substrates to adaptable nanoparticles like gold nanostars and nanorattles. The "Inverse Molecular Sentinel" (iMS) biosensing technology uses surface-enhanced Raman scattering (SERS) to detect nucleotide biomarkers associated with diseases ranging from acute infections to several types of cancer. We have also developed SERS-based nanochip systems capable of detecting DNA targets related to infectious disease biomarkers such as HIV, malaria, and dengue, promising advancements in global health diagnostics. Further, nanorattle-based biosensors are designed as "lab-in-a-stick" devices for rapid head and neck cancer diagnosis. Other technologies include plasmonics-enhanced lateral flow immunoassay systems, smartphone-based biosensing, and implantable biosensors or "smart tattoo" systems. These nanoplasmonics biosensors open new frontiers to rapid, simple, and effective detection systems for biomedical diagnostics.

Indexed as

BiosensorsCancer biomarkersGlobal healthLiquid biopsyNanoplasmonicsPoint-of-careRamanSERS

Identifiers

PMID40607139
PMCPMC12220822

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.