ArticleFrontiers in nutrition2025
Exploring the association of vitamin B12 deficiency and dental health in older adults.
Article in Frontiers in nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Vitamin B12 plays a crucial role in overall health, yet its impact on dental health, particularly dental caries, remains underexplored. Older adults are at an increased risk of vitamin B12 deficiency and dental disease, but the relationship between these two factors is not well understood. This study examines the association between serum vitamin B12 levels and dental health in older adults using data from the NHANES 2011-2014 cycles. Methods: A cross-sectional analysis was conducted using NHANES data from 1,907 participants aged 65 and older. Serum vitamin B12 levels were categorized as normal (>221 pmol/L), marginal (148-221 pmol/L), and deficient (<148 pmol/L). Dental status was assessed using the Decayed, Missing, and Filled Teeth (DMFT) index based on NHANES dental health examinations. Poisson regression models evaluated associations between vitamin B12 levels and DMFT scores, adjusting for age, sex, race/ethnicity, education, and income. Results: Lower vitamin B12 levels were significantly associated with higher DMFT scores ( Conclusion: These findings suggest that vitamin B12 deficiency may contribute to a greater lifetime burden of dental disease in older adults. Further research is needed to explore causal mechanisms and assess whether vitamin B12 supplementation could be a preventive measure for maintaining dental health in aging populations.
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