Evidence map›Paper›PMID 40607007›Full record

ArticleAddictive behaviors reports2025

A short, animated storytelling video to reduce addiction stigma: A pilot randomized controlled trial.

Maxwell Klapow, Misha Seeff, Maya Adam, Merlin Greuel, Daniel Hoffman, Jessica R Rogge, Andrew Gordon, Till Bärnighausen, Doron Amsalem

Abstract read
In one paragraph

Article in Addictive behaviors reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Maxwell KlapowDepartment of Experimental Psychology, University of Oxford, Oxford, UK.
Misha SeeffUnited World College Maastricht, Maastricht, the Netherlands.
Maya AdamDept. of Pediatrics, Stanford University School of Medicine, Stanford, CA, USA.
Merlin GreuelHeidelberg Institute of Global Health, Heidelberg University, Heidelberg, Germany.
Daniel HoffmanMathematical Institute, University of Oxford, Oxford, UK.
Jessica R RoggeBoston University, College of Arts and Sciences, Boston, MA, USA.
Andrew GordonProlific Academic, London, UK.
Till BärnighausenHeidelberg Institute of Global Health, Heidelberg University, Heidelberg, Germany.
Doron AmsalemDept. of Psychiatry, Columbia University Vagelos College of Physicians and Surgeons, NY, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and aims: Public stigma towards people with addiction negatively impacts help-seeking, treatment and recovery. This pilot study tested the feasibility of conducting a large-scale, online trial to measure the effect of a short, animated storytelling (SAS) stigma reduction video, with and without soundtrack, on addiction stigma, optimism, warmth towards people with addiction, and hopefulness at two timepoints (immediately post-exposure and 14 days later). Design: We used a parallel group, three-arm randomized controlled trial (RCT). Setting: We conducted this fully online study on the Prolific Academic research platform (participant recruitment) and the Qualtrics survey platform (data collection). Participants: We recruited 631 English-speaking adult participants, aged 18-49, residing in the United States. Interventions: Intervention group A received the SAS video intervention. Intervention group B group received the SAS video intervention without sound. The control group received written information about global addiction prevalence, estimated to be time-equivalent with the video interventions. Measurements: We measured participant retention rate at the two-week follow-up to determine the feasibility of conducting the definitive trial. Our co-primary outcomes were addiction stigma, optimism, warmth towards people with addiction and hopefulness, measured using an abbreviated 18-item version of the Attribution Questionnaire (AQ-18), the Brief García's Interactive Optimism Scale (BIOS-G), a stigma thermometer and a visual analogue scale (VAS). We used repeated-measures ANOVA to assess group-by-time interactions and compared changes from baseline to post-intervention. Participants completed follow-up surveys 14 days post-intervention. Findings: The retention rate from baseline to follow-up was 88.0 %. Exposure to both the video with sound and without sound resulted in significant positive changes compared to the control group, for pity [F (4,1046) = 3.26, η Conclusions: This pilot study demonstrates the feasibility of proceeding with our registered, largescale, multi-country, online RCT. The significant effect observed in a relatively small pilot population, after a single exposure to this 2.5 min SAS intervention aimed at reducing addiction stigma, was unanticipated and is worthy of highlighting. A larger sample size will adequately power the full trial to detect both immediate effects and their potential durability over time, in various global settings.

Indexed as

AddictionAnimated storytellingOnline trialSASShortStigmaVideo

Identifiers

PMID40607007
PMCPMC12214250

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.