Evidence map›Paper›PMID 40606830›Full record

ArticleFrontiers in fungal biology2025

Impact of CD11c

Mariia Pavelchenko, Svyatoslav Shalyapin, Sergey Portnov, Andrey Bogorodskiy, Elena Bolkhovitina, Vitalii Shevchenko, Alexander Sapozhnikov, Valentin Borshchevskiy, Marina Shevchenko

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in fungal biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Mariia PavelchenkoLaboratory of Cell Interaction, Immunology Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Svyatoslav ShalyapinLaboratory of Cell Interaction, Immunology Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Sergey PortnovLaboratory of Cell Interaction, Immunology Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Andrey BogorodskiyResearch Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia.
Elena BolkhovitinaLaboratory of Cell Interaction, Immunology Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Vitalii ShevchenkoDepartment of Applied Mathematics, Tikhonov Moscow Institute of Electronics and Mathematics National Research University Higher School of Economics, Moscow, Russia.
Alexander SapozhnikovLaboratory of Cell Interaction, Immunology Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.
Valentin BorshchevskiyResearch Center for Molecular Mechanisms of Aging and Age-Related Diseases, Moscow Institute of Physics and Technology, Dolgoprudny, Russia.
Marina ShevchenkoLaboratory of Cell Interaction, Immunology Department, Shemyakin and Ovchinnikov Institute of Bioorganic Chemistry, Russian Academy of Sciences, Moscow, Russia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Inhaled conidia of the opportunistic fungi Methods: Therefore, we employed advanced imaging techniques, including immunohistochemistry, optical clearing, and confocal laser scanning microscopy, to map Results: Our findings revealed that while the majority of conidia reached the alveolar space in both groups, neutropenic mice showed significantly higher conidial concentrations in bronchial branches, particularly in the main bronchus, compared with immunocompetent mice. Simultaneously, in the conducting airway mucosa of neutropenic mice, CD11c Discussion: Thus, detailed mapping of the conidial distribution patterns provides crucial insights into the spatial aspects of antifungal treatment in neutropenic patients. The enhanced contribution of CD11c

Indexed as

Aspergillus fumigatus conidia distributionconducting airway mucosaconfocal laser-scanning microscopyimmune cell–pathogen interactionsinvasive aspergillosis mouse modelmacrophagesneutrophil depletionwhole-mount lung imaging

Identifiers

PMID40606830
PMCPMC12213632

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.