ArticleCerebral circulation - cognition and behavior2025
Effect of liquiritin on the expression of BDNF, Bax, and Bcl-2 in the hippocampus of post-stroke depression rats.
Article in Cerebral circulation - cognition and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
1 citing paper in PubMed.
- Basic and clinical research on acupuncture for post-stroke depression: A narrative review.World journal of methodology · 2026Review
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Authors and funding
5 authors.
Funding
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Abstract
Aims: The study intended to explore the therapeutic effect of liquiritin on PSD rats and its role in the pathogenesis of PSD. Methods: The stroke model was established via middle cerebral artery occlusion, and the PSD model was created using chronic unpredictable mild stress combined with isolated feeding. The expressions of BDNF, Bax, and Bcl-2 proteins in the hippocampus of rats were detected using Western blot and immunofluorescence staining after 6 weeks of modeling. Results: The weight, sucrose consumption and activity of the PSD rats decreased ( Conclusions: Liquiritin is capable of inhibiting neuronal apoptosis in the hippocampus of PSD rats to improve depression symptoms. This improvement may be achieved by reducing the expression of Bax and increasing the expressions of Bcl-2 and BDNF in the hippocampus of PSD rats.
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