Evidence map›Paper›PMID 40606543›Full record

ArticleAcute medicine & surgery

Bickerstaff brainstem encephalitis developed quickly after COVID-19 infection.

Daiki Mori, Takahiro Yamada, Hiroshi Fukuma, Shota Nakao, Tetsuya Matsuoka

Abstract read
In one paragraph

Article in Acute medicine & surgery. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Daiki MoriRinku General Medical Center Senshu Trauma and Critical Care Center Osaka Japan.ORCID https://orcid.org/0009-0009-4556-0136
Takahiro YamadaRinku General Medical Center Senshu Trauma and Critical Care Center Osaka Japan.ORCID https://orcid.org/0000-0002-5391-6202
Hiroshi FukumaRinku General Medical Center Senshu Trauma and Critical Care Center Osaka Japan.
Shota NakaoRinku General Medical Center Senshu Trauma and Critical Care Center Osaka Japan.
Tetsuya MatsuokaRinku General Medical Center Senshu Trauma and Critical Care Center Osaka Japan.ORCID https://orcid.org/0000-0002-9913-8186

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Bickerstaff brainstem encephalitis (BBE) is an autoimmune disease characterized by impaired consciousness, ophthalmoplegia, and ataxia. We report two cases of BBE following COVID-19. Case Presentation: Case 1: A 51-year-old male was diagnosed with COVID-19 4 days after fever. He had prolonged loss of consciousness, and developed ophthalmoplegia and ataxia. He was treated with steroids and immunoglobulin, which improved his consciousness. Case 2: A 28-year-old female was diagnosed with COVID-19 because of fever 4 days after contact with a COVID-19 patient. She suffered from prolonged loss of consciousness, ophthalmoplegia, and myoclonus. She was treated with steroids, immunoglobulin, and plasmapheresis, which ameliorated her consciousness. Conclusion: Both patients developed central nervous system (CNS) symptoms within a week of COVID-19 onset, indicating that BBE develops immediately after prior infection. This disease should be considered if CNS symptoms appear rapidly after COVID-19.

Indexed as

autoimmune diseasecentral nervous system symptomsearly diagnosisprior infection

Identifiers

PMID40606543
PMCPMC12214469

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.