Evidence map›Paper›PMID 40606514›Full record

ArticleEuropean urology open science2025

Intravesical Injection of Bulking Agents: Validation of the Ghent University Hospital Porcine Teaching Model.

Caroline Jamaer, Manon De Loof, Jolien Van der Jeugt, Ellen Vandamme, Mieke Waterschoot, Raimund Stein, Matthieu Peycelon, Berk Burgu, Erik Van Laecke, Piet Hoebeke and 1 more

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In one paragraph

Article in European urology open science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Caroline JamaerDepartment of Urology, Ghent University Hospital, ERN eUROGEN accredited center, Ghent, Belgium.
Manon De LoofDepartment of Urology, Ghent University Hospital, ERN eUROGEN accredited center, Ghent, Belgium.
Jolien Van der JeugtDepartment of Urology, Ghent University Hospital, ERN eUROGEN accredited center, Ghent, Belgium.
Ellen VandammeDepartment of Urology, Ghent University Hospital, ERN eUROGEN accredited center, Ghent, Belgium.
Mieke WaterschootDepartment of Urology, Ghent University Hospital, ERN eUROGEN accredited center, Ghent, Belgium.
Raimund SteinDepartment of Urology, University of Mainz School of Medicine, Mainz, Germany.
Matthieu PeycelonDepartment of Pediatric Surgery and Urology, National Reference Center for Rare Urinary Tract Malformations (CRMR MARVU), ERN eUROGEN accredited center, Robert-Debré University Hospital, APHP, GHU North, Health Simulation Department, iLumens, UMR INSERM 1141 NEURODEV, Université Paris Cité, Paris, France.
Berk BurguDepartment of Urology, Ankara University Hospital, Ankara, Türkiye.
Erik Van LaeckeDepartment of Urology, Ghent University Hospital, ERN eUROGEN accredited center, Ghent, Belgium.
Piet HoebekeDepartment of Urology, Ghent University Hospital, ERN eUROGEN accredited center, Ghent, Belgium.
Anne-Françoise SpinoitDepartment of Urology, Ghent University Hospital, ERN eUROGEN accredited center, Ghent, Belgium.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and objective: Intravesical injection of bulking agents is an endoscopic treatment for vesicoureteral reflux (VUR) in children. The success of the procedure depends on the surgical technique; yet, few validated simulators exist for training. This study aimed to assess the face and content validity of a porcine bladder model for training in endoscopic VUR correction. Methods: The Ghent University Hospital endoscopic reflux correction simulator, an ex vivo porcine bladder, was developed. Dextranomer/hyaluronic acid (Dx/HA) was used for bilateral subureteric injection. Participants from the 2022 European Society for Paediatric Urology Congress in Belgium completed a questionnaire evaluating the model's realism (face validity) and training effectiveness (content validity). Differences between experts and nonexperts were analyzed using the Mann-Whitney Key findings and limitations: A total of 39 participants (12 experts and 27 nonexperts) evaluated the model, including urologists (53.8%), surgical trainees (35.9%), and pediatric surgeons (12.8%). The simulator showed high face validity, with a median Likert score of 5/5. The experts rated the realism significantly higher than the nonexperts ( Conclusions and clinical implications: The Ghent University Hospital porcine bladder model closely mimics a human bladder and is considered valuable for teaching the Dx/HA procedure. Further studies should examine whether this leads to clinically meaningful improvements in skill performance. Patient summary: A high fidelity simulator is developed and validated in this study to improve surgical skills in endoscopic correction of vesicoureteral reflux, thereby improving patient outcomes.

Indexed as

Dextranomer/hyaluronic acid injectionSimulatorTeaching toolValidityVesicoureteral reflux

Identifiers

PMID40606514
PMCPMC12209941

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.